complications of liver transplantation

[osman850]

     I am 45 years old ,male,I have been recived live donner transplant for end stage liver cirrhosis due to hepatitis C .Transplantation was done in Egypt 25-5-2008, I did very well for 2 months and then ler enzyme start to rise , liver biobsy revealed mild rejection, adjustment of tacrolimus was done.but liver enzymes cntinue to rise.MRCP was done and reveaed mid  dilatation of hepatic ductes and ERCP and stenting was done 1.5 month ago.
      Although bilirubin both direct and total, albumin, prothrombin, C.B.C, urea and creatinine all are within normal, liver enzyme(GGt=1400,ALT=170 and AST=200) continue to rise and HCV 1800000 .
      The team decided another biobsy and repeat MRCP but I lost confidence in them.
       What is your opinion, please rapid answer .  NB( FK level =9.5)

[Thomas D Schiano, MD]

i agree with the above comment.  It must likely is HCV.  biliary stricturing is common after live donor liver transplantation so that must be thororoughly sorted out before HCV is contemplated.

[lyncord]

hmmmn, you know same thing happen to my husband..he had LDLT and they did stenting on him. where is the stent located?  mostly those numbers are related to hcv recurrence. youre bilirubin you said is normal, how about you alkaline phosphates.
do not worry too much,, my husband ggt 2mos post op was 2400 and the rest is pretty high too.