Aa
Aa
A
A
A
Close
Avatar universal

lowering rejection drugs

Based on ALT/AST continuing to rise to the 300/400 level, and not rejection but hcv, what is the general action taken.  Do you lower the prograf or cellcept and monitor closely?  What is your experience in this scenario as far as the outcome?
3 Responses
Sort by: Helpful Oldest Newest
517301 tn?1229797785
MEDICAL PROFESSIONAL
the changes hould be obvious unless there are components of both seen in the same biopsy.  an expert liver pathologist is needed in these circumstances
Helpful - 0
Avatar universal
How does the doctor who analyzes the biopsy tell the difference between rejection and hcv inflammation?  What is the difference under the glass?
Helpful - 0
517301 tn?1229797785
MEDICAL PROFESSIONAL
if a liver biopsy shows that this is recurrent HCV and not rejection and antiviral teatment is not to be started, then lowering the immunosuppression somewhat is the way to go.  if interferon is to be used to treat the HCV then the immunosuppression cannot be too low or rejection will be precipitated.
Helpful - 0

You are reading content posted in the Liver Transplant Forum

Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.