Liver Transplant Forum
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal

monitoring for lymphoma while taking cellcept

Should the transplant team/doctor monitor liver transplant patients taking cellcept post liver transplant over time?  Is there a significant threat of cellcept causing lymphoma?
2 Responses
517301 tn?1229797785
i agree with the above comments.  however, there is no documented increased cancer risk specifically with the use of long-term mycophenolate use.  the less immunosuppression one takes over time, the better however.
Avatar universal
As a liver transplant recipient myself, my advice is not to rely on your transplant team "Monitoring" as your first line of defense of cancer post transplant. Life after a liver transplant requires the recipient to be aware of the increased risk of infections and cancer. All immunosuppressants work by decreasing the activity of certain cells that make up part of the immune system to help reduce the risk of organ transplant rejection. CellCept weakens your immune system, which may decrease your ability to fight illness or infection. It may also increase the risk of certain types of cancer. Although almost all cancers can occur, skin cancer and non-Hodgkin’s lymphomas are the most frequent. Skin cancer of the non-melanomic variety, especially squamous cell cancer, is the most frequent of all cancers.  Its incidence increases as the duration of immunosuppression increases.  Although metastasis and death from these cancers are uncommon in the general population, they can be fatal in the transplant population.
All post transplant patients should be alert to the early detection of cancer. This can be helped by monthly breast, testicular and skin self examination and routine medical check-ups. PAP smears, breast exams, testicular exams, and skin cancer screening should be done by your physician every year. Other general measures should also be taken. These include:
• Reduce sun exposure
• Stop smoking
• Follow a balanced diet plan
• Get enough exercise

Life can be very good post transplant, but you must work on being aware of those things that increase your risk of serious illness. Your transplant team can help identify these, but it becomes your job to follow-up on them, especially as time goes on. With luck you will be seeing less and less of your transplant team and more follow-up is with your own physician. You went through a lot to get the transplant, now is not the time to become complacent.

Popular Resources
For people with Obsessive-Compulsive Disorder (OCD), the COVID-19 pandemic can be particularly challenging.
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.
These common ADD/ADHD myths could already be hurting your child
This article will tell you more about strength training at home, giving you some options that require little to no equipment.
In You Can Prevent a Stroke, Dr. Joshua Yamamoto and Dr. Kristin Thomas help us understand what we can do to prevent a stroke.