Hi,
With fever, lymph nodes in the chest, itching, weakness, sweating, and illness, the main diagnosis that needs to be considered is a lymphoma. This is a condition where lymph glands swell up, and may need chemotherapy, radiation, or both during treatment. Results of treatment are usually good.
You have been scheduled for a biopsy, and the diagnosis will be either confirmed or excluded when that report is available.
Of course, the possibility of a non-cancer diagnosis (for example infection, tuberculosis, sarcoidosis, etc) is always there. This is especially true because you have had illness for two years, and many tests have been done, with no evidence yet of any cancer. Pl keep us posted about your test results.
All the best, and God Bless!
I should have noted that I am 40 yr old female, non-smoker. Been sick for couple years with most problems pointing toward auto-immune, but Rheum not yet able to make definitive diagnoses. Hope that info helps.