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How do you know when you are cured for good?

My son has been diagnosed with Lyme  (Western Blot: 24 points: p100, vsE, p58, p41, P39, p18 Baf, p 18Bba ) after a bite this summer. He had 3 weeks of antibiotics. He still has some symptoms but the doctor says that he is cured. Is there a test to confirm that he is cured?
Thank you very much for your answers.
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