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Lyme Disease Can Be Prevented With New Shot, Study Suggests
from science daily 2008
The researchers found that a new formulation of doxycycline hyclate that is programmed to release the drug over a 20 day period is 100% effective.
"The underlying copolymer formulation has been in use for over 20 years. It has no adverse effect on humans and it can be programmed to release a drug over several weeks to several months," says Dr Zeidner. "We plan to test the doxycycline formulation to develop different release kinetics and delivery methods. For example, a slow release patch could be used in conjunction with current recommended protection against ticks, such as repellents and personal tick checks."
The researchers found that a new formulation of doxycycline hyclate that is programmed to release the drug over a 20 day period is 100% effective.
"The underlying copolymer formulation has been in use for over 20 years. It has no adverse effect on humans and it can be programmed to release a drug over several weeks to several months," says Dr Zeidner. "We plan to test the doxycycline formulation to develop different release kinetics and delivery methods. For example, a slow release patch could be used in conjunction with current recommended protection against ticks, such as repellents and personal tick checks."
Looks like they didn't get it working. It still would require two rounds, though. The IDSA only treats early Lyme for 21 days, but I have read estimates by LLMDs that it has a 10-25% treatment failure rate. ILADS says you need at least 28 days to make sure you got it all.
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