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My daughters western blot showed positive IgG band 18 and 23 everything else negative. Of course CDC says negative. Can these two bands mean anything else? This is all so confusing, I just want to know if she has Lyme or not. What is everyones opinion on this.
Agree with Jackie. Get to an LLMD and get on lymenet dot org (flash discussions.)
Only an LLMD can get your daughter well. She has it.
watch the 2008 documentary Under our Skin (www.underourskin.com) You can also see clips on Youtube.
Only an LLMD can get your daughter well. She has it.
watch the 2008 documentary Under our Skin (www.underourskin.com) You can also see clips on Youtube.
Welcome --
According to the website truthaboutlyme [dot] com (printed down in May 2009, haven't checked it again since then):
"[band] 18: highly specific to Lyme (Many LLMDs ssay if this band is positive, you have lyme)"
and
"[bands] 23-25: outer surface protein C (OspC), specific for Bb [Borrelia burgdorferi, the Lyme bacteria]"
Also: "IgG positive means previous exposure to the bacteria or older infection of Lyme." That means you have Lyme, but it's not a brand new infection.
This article also says, "There are nine known Bb genus specie specific KDA Western Blot antibodies (bands): 18 23 30 31 34 37 39 83 and 93. Only one of these Bb genus specie specific bands is needed to confirm that there is serological [blood] evidence of exposure to the Bb spirochete and can confirm a clinical diagnosis of Lyme disease. (More into pages 12 & 13 "Western Blot Made Easy": http:// www [dot] publichealthalert [dot] org/PHA%20JUNE%2007 [dot] pdf )
Other bands may or may not be Bb/Lyme, and some are clearly not Lyme; but the two you name are in the Bb category for certain.
If you have not consulted an LLMD, I would suggest you do so, since this sounds like an older infection and therefore more entrenched. That doesn't mean treatment will not be effective, but it means longer treatment may be advisable, and a nonLLMD is less likely to provide that.
Also, if it were my daughter, I would seek advice from an LLMD about other tests for possible coinfections carried by the same tick that bit your daughter. The tests are different, and often so are the treatments.
Best wishes -- let us know how your daughter does.
According to the website truthaboutlyme [dot] com (printed down in May 2009, haven't checked it again since then):
"[band] 18: highly specific to Lyme (Many LLMDs ssay if this band is positive, you have lyme)"
and
"[bands] 23-25: outer surface protein C (OspC), specific for Bb [Borrelia burgdorferi, the Lyme bacteria]"
Also: "IgG positive means previous exposure to the bacteria or older infection of Lyme." That means you have Lyme, but it's not a brand new infection.
This article also says, "There are nine known Bb genus specie specific KDA Western Blot antibodies (bands): 18 23 30 31 34 37 39 83 and 93. Only one of these Bb genus specie specific bands is needed to confirm that there is serological [blood] evidence of exposure to the Bb spirochete and can confirm a clinical diagnosis of Lyme disease. (More into pages 12 & 13 "Western Blot Made Easy": http:// www [dot] publichealthalert [dot] org/PHA%20JUNE%2007 [dot] pdf )
Other bands may or may not be Bb/Lyme, and some are clearly not Lyme; but the two you name are in the Bb category for certain.
If you have not consulted an LLMD, I would suggest you do so, since this sounds like an older infection and therefore more entrenched. That doesn't mean treatment will not be effective, but it means longer treatment may be advisable, and a nonLLMD is less likely to provide that.
Also, if it were my daughter, I would seek advice from an LLMD about other tests for possible coinfections carried by the same tick that bit your daughter. The tests are different, and often so are the treatments.
Best wishes -- let us know how your daughter does.
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