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DOUBLE POSITIVE-maigraines?
i found out today that I AM POSITVE FOR heterozygouse MTHFR C677T and A1298C mutaions, I'm also negative for factor five liden. My 19 month old daughter also has double postives and factor five liden from her father. My husband in negative for MFTFR and positive for factor five, thrombin mutaion.
I had a miscarage in my teens, a few days after I found out I was expecting. I too was not ready and young and tried to live on, I had no problems and took oral conctaceptive. Years later I was rushed to the ER with suspected appendisitis. Turn out to be rupturing ovarian cycst, i was diagnosised with poly cycstic ovarian syndrom and started metformin and contnuied the pill. My cycles were regular and light.
In 2007 I was rear ended at 45 mph and now take narcotices daily, although on the pill I got pregnate and now have my beatul daughter as of may 2009. My husband since 02 2010 was in the icu with left calf dvt and 2 PE's.
Our daughter was tested for lead and aniemia i mentioned her dad had favtor five and they added the test to her lab slip, week later they called me with a positve. We saw a ped. hemotlogist and found out she has fator five and MFTHR. They but her on folic acid daily liuid poly-vit-sol for iron and b6. We are told she is high rick for clotts. Im worried her dady tajkes 12mg of Coumidin daily(average 2-3 mg daily, he ahs very thick blood).
We have been trying to have another child since our first was born, I was starting to get frusterated, but i was only tested for this becasue my daughter was postive and husband negative, how common is this? I also have stage 2 liver disease specialist I Hepotology dr for and was recent told I have high testoserone levels and tested negative for cushing by my endocrinologist. he told me to see an o specialist and start on Cloumid along with metformin for my PCOS and vit e for my liver and start prenatal vitamins. I'm gonna go for it and see if to works, god willing.
I suffer from sever migraines for the last 3 years. So frequesnt and sever I don't often leave home. My daughter has a playground in the yard and we alwo the other kids to use it so she has company, I'm scared to drive. or get suck becasue I cant drive back home, they last hours, i see spotts and nausea. does anyone else get migraines?
I had a miscarage in my teens, a few days after I found out I was expecting. I too was not ready and young and tried to live on, I had no problems and took oral conctaceptive. Years later I was rushed to the ER with suspected appendisitis. Turn out to be rupturing ovarian cycst, i was diagnosised with poly cycstic ovarian syndrom and started metformin and contnuied the pill. My cycles were regular and light.
In 2007 I was rear ended at 45 mph and now take narcotices daily, although on the pill I got pregnate and now have my beatul daughter as of may 2009. My husband since 02 2010 was in the icu with left calf dvt and 2 PE's.
Our daughter was tested for lead and aniemia i mentioned her dad had favtor five and they added the test to her lab slip, week later they called me with a positve. We saw a ped. hemotlogist and found out she has fator five and MFTHR. They but her on folic acid daily liuid poly-vit-sol for iron and b6. We are told she is high rick for clotts. Im worried her dady tajkes 12mg of Coumidin daily(average 2-3 mg daily, he ahs very thick blood).
We have been trying to have another child since our first was born, I was starting to get frusterated, but i was only tested for this becasue my daughter was postive and husband negative, how common is this? I also have stage 2 liver disease specialist I Hepotology dr for and was recent told I have high testoserone levels and tested negative for cushing by my endocrinologist. he told me to see an o specialist and start on Cloumid along with metformin for my PCOS and vit e for my liver and start prenatal vitamins. I'm gonna go for it and see if to works, god willing.
I suffer from sever migraines for the last 3 years. So frequesnt and sever I don't often leave home. My daughter has a playground in the yard and we alwo the other kids to use it so she has company, I'm scared to drive. or get suck becasue I cant drive back home, they last hours, i see spotts and nausea. does anyone else get migraines?
Jw84,
I should also mention I have the same MTHFR diagnosis as you do - compound heterozygous (meaning positive one copy C677T and positive one copy A1298C). Hopefully we can compare stories and share more information on the topic.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
Sincerely,
Sandi (Dragon1973)
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator;
MTHFR Group Forum Founder/Moderator;
Pregnancy: June 2011 Community Leader
I should also mention I have the same MTHFR diagnosis as you do - compound heterozygous (meaning positive one copy C677T and positive one copy A1298C). Hopefully we can compare stories and share more information on the topic.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
Sincerely,
Sandi (Dragon1973)
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator;
MTHFR Group Forum Founder/Moderator;
Pregnancy: June 2011 Community Leader
Hello JW84,
Wow, first let me say that is quite the lengthy list! With all that is going on, I congratulate you on your past pregnancies and births. While not a medical expert, I can tell you this - I have suffered with nearly all the same things as you from the cystic ruptures, which led them to determine the PCOS, the migraines (which to this day I am not sure if they are due to the MTHFR or from my Pituitary tumour) to the hormone problems and also the testing neg for Cushings syndrome. However, there is a ton of research studies that suggest that MTHFR (specifically C677T variant) is responsible for migraines and aura migraines. So it's hard to say but I wouldn't doubt it. I definitely get the spots and nausea, have had it all my life and don't think I had the pituitary tumour all my life. Interestingly though, I also take narcotic medications for a serious back injury I sustained from work, so perhaps it is a combination of things.
I am curious, knowing that you have the variant, and also the possibility for clotting problems such as thrombosis, do you take a low dose baby aspirin at all or Lovenox? I found it quite necessary to take these (or at the very least the high level Folic acid and baby aspirin) in order to conceive. Without them, I either had miscarriages or implantation failures (early pregnancy loss).
Feel free to message me directly at any time.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
Sincerely,
Sandi (Dragon1973)
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator;
MTHFR Group Forum Founder/Moderator;
Pregnancy: June 2011 Community Leader
Wow, first let me say that is quite the lengthy list! With all that is going on, I congratulate you on your past pregnancies and births. While not a medical expert, I can tell you this - I have suffered with nearly all the same things as you from the cystic ruptures, which led them to determine the PCOS, the migraines (which to this day I am not sure if they are due to the MTHFR or from my Pituitary tumour) to the hormone problems and also the testing neg for Cushings syndrome. However, there is a ton of research studies that suggest that MTHFR (specifically C677T variant) is responsible for migraines and aura migraines. So it's hard to say but I wouldn't doubt it. I definitely get the spots and nausea, have had it all my life and don't think I had the pituitary tumour all my life. Interestingly though, I also take narcotic medications for a serious back injury I sustained from work, so perhaps it is a combination of things.
I am curious, knowing that you have the variant, and also the possibility for clotting problems such as thrombosis, do you take a low dose baby aspirin at all or Lovenox? I found it quite necessary to take these (or at the very least the high level Folic acid and baby aspirin) in order to conceive. Without them, I either had miscarriages or implantation failures (early pregnancy loss).
Feel free to message me directly at any time.
In addition to anything I have mentioned, please keep in mind, that while I or others may have extensive knowledge in many areas, you should always seek professional medical advice from your own physician, as it pertains to medical conditions or concerns.
Good luck, and if you have any other questions that I can help you with, please feel free to message me directly.
Sincerely,
Sandi (Dragon1973)
MedHelp Genetics Community Leader;
Children - Special Needs Community Leader;
Down syndrome Community Leader & Ds Group Forum Founder/Moderator;
MTHFR Group Forum Founder/Moderator;
Pregnancy: June 2011 Community Leader
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