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Avatar universal

Please help!

A few months ago I was put on Mirtazapine 15mg, on top of my Effexor 112.5mg. I started noticing memory issues. Recalling names of certain people, objects and some terms. My doctor upped my dose to 30mg thinking that the side effects would go away. They did not. About a month ago I came off the Mirtazapine, and still experience memory issues.

I have read over and over again in forums of this happening to people, but when I told my doctor he claims it’s not from the medicine. (even though that’s the only variable that has changed).

He wants me to go for special memory testing, for my frontal lobe.


I am really freaking out. I have my girlfriend test my memory and it seems to be getting better, but I am still very nervous.

Has anyone else had, or heard of this happening?

What could be wrong with my brain?

Thanks. I am currently in the process of getting my anxiety under control in other ways, without medication.
1 Responses
Avatar universal

Hello there,

I just finished reading your comments. I know that Effexor is an antidepressant. I used to take it myself at one point in my life but the side
effects of Effexor were uncomfortable for me and I requested that I be
given a new medication and I was and that one works better for me.
A family member of mine is on Effexor and it works fine for her.
Anyway, you're asking about the drug Mirtazapine. I am looking at a
book of mine as a resource. The book is called The Canadian Guide to
Drugs and Supplements. It's published by Reader's Digest.
The product names for Mirtazapine are Gen-Mirtzapine, Remeron,
Remeron RD, Rhoxal-Mirtazaphine.

" Mirtazaphine is an antidepressant chemically different  that the SSRIs
and tricyclic antidepressants. It is used in the treatment of mild to moderate
depression. Mirtazaphine is as effective as other antidepressants. It can
cause drowsiness and weight gain. It may also  cause a decrease in blood pressure on quickly sitting or standing up. Caution should be used; stand
up slowly, while supporting oneself.  It is best to take mirtazaphine in the
evening prior to sleep. Usual adult dosage range  15 -45 mg.
Possible Adverse Effects of Mirtazapine
Drowsiness                                           common
Dizziness                                               common
Increased appetite/weight gain              common
Muscle weakness                                  rare
Dry mouth                                             common
Constipation                                          rare
Tiredness/fatigue                                   rare

I am not a doctor, but this seems like a lot of antidepressants ie. Effexor,
112.5 mg. and Mirtazapine, 30 mgs.  This is just an observation, not a
medical opinion.  

" Venlafaxine ( product names are Effexor, Effexor XR) is an antidepressant
with a chemical structure unlike any other available antidepressant.
It combines the therapeutic properties of both the tricyclic antidepressants
and selective serotonin reuptake inhibitors ( SSRIs) , without
anticholinergic adverse effects.
Possible Adverse Effects of Effexor

Nausea                                        common
Restlessness/ Insomnia              common
Weakness/blurred vision             common
Drowsiness/dizziness                  common
Decreased appetite                      rare
Sexual dysfunction                       rare
Rash/ Itching                                rare
High blood pressure                     rare

You say you are currently in the process of getting your anxiety under
control without medication.  I am hoping you have not just stopped
taking Effexor without consulting your doctor. Stopping abruptly can
cause withdrawl symptoms. This applies to both of these drugs.
Okay, this is my personal opinion. Based on your comments, you
might consider finding another doctor. Based on what you've said, I don't
think you need to go for special memory testing. I think perhaps you
were over medicated. Is this doctor you speak of your GP or a psychiatrist ?
If any of this has helped, I'm glad to have been of help to you.  Eve
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