I had a spare total hysterectomy and bilateral silpango oophorectomy two years ago no hrt in the past yr my body has all but given up 40lbs later severe joint pain and mood,? Depression doesn't begin to describe the mental anguish I'm in is there any hope I can't find any motivation to try to the hot flashes nausea are terrible but the pain is non stop my PCP apparently doesn't have a clue I can't take much more of this