Hello
Recently Complete blood profile was studied in which it was noticed that my ESR was 65mm/hr and CRP of 192mg/l. Howevr, my hamoglobin is 15.6,RBC,HEMATOCRIT,MCV,MCHC,RDW,PLATELETS COUNT,WHITE BLOOD CELLS are normal.
At the time the test was done i was having fever with joint pains and cough, with chills in night.
Please advic me whether ESR and CRP elevation is a serious issue or not with respect to other things being normal.
Regards
RR
The erythrocyte sedimentation rate (ESR) is a nonspecific indicator of inflammation. An ESR of 50 is quite high; most persons with such a level would be fairly obviously sick--perhaps fever, weight loss, cough, etc. A large number of infections, cancer, and various autoimmune diseases can do it. Taking a wild guess from your name, if you are in a developing country, various parasitic infestations might be possible. Or if you are in a setting where HIV is common and you are at risk, that possibility needs to be checked. Did you have a CBC (complete blood count)? Most people with such a high ESR have anemia and/or abnormal white blood counts.
If you feel well and are outwardly well, it's a good bet there was an error in the test and nothing is wrong. In addition to repeat ESR, you could have a C-reactive protein test (CRP), a more modern test for systemic inflammation. In any case, follow up with your health care provider until you know it is normal or you know the cause.
HHH, MD