Hello, I have had menstrual migraines for over 30 years and as I get closer to menopause, things are getting worse. I had a hysterectomy last July and have been taking.25mg estradiol gel every night and when I first started taking it, it seemed like the headaches were not so bad. Now I am wondering if I should bump it up to .50 because not only do I seem to be constantly battling a headache (that may or may not turn in to a migraine) but I am really depressed to the point where I can feel my body ache from it. I am 5;5", 132lb and feel hopeless. Anybody have any ideas about whether bumping the estrogen might be good? Thank you!