1548924 tn?1296255044

Are No Brain Lesions on MRI Common with MS Diagnosis?

Thank you for taking time to read my question.  I've had the Brain scan checking for lesions for possible MS diagnosis and it came back negative.  My Dr still thinks I have MS (so do I) and we've ruled out most other causes with all the typical bloodwork etc.   I have 85% of the Symptoms for MS and the first 'episode' I had was at age 26 several months after having Scarlet Fever.  My legs just quit working.  It was very brief and only lasted about 10 seconds until I fully recovered, but it scared me.  No diagnosis at the time from just that one symptom.  I'm 45 years old now and have been experiencing all these weird symptoms that came and went over the last 19 years and I never put it all together before...as in ONE thing causing ALL of it, until my legs quit working again about 4 months ago and it's happened again twice since then.  Recovery is usually just within seconds (so far).  My next tests are the neck/spine MRI and possible Spinal Tap to confirm a diagnosis.  I have no health insurance so I hafta wait for those tests.  

My Question is this:  

**How common is it to have no lesions on an MRI...brain or otherwise...and still have an accurate MS diagnosis?
Best Answer
1382889 tn?1505071193
Not sure it matters how common it is or not, the fact is is that it is entirely possible to have no brain lesions and get a dx of MS.  It happened to me.  18 yrs worth of brain MRI's all negative. Finally they did spinal MRI (cervical and t) and found lesions. Got dx right then and there.

4 Responses
Sort by: Helpful Oldest Newest
1394601 tn?1328032308
I was like you.  Years later putting together things that happened...not even reporting them to a doctor.  My first sign was  hot burning feet.  The next a burning thigh.  I did see my family doctor on that issue.  He suggested a neuro and I didn't follow up.  The next was exactly what is happening to you.  I began freezing in place unable to move.  It happened in the middle of a shopping center...as I was paying for a purchase.  Another time on a ladder and unable to move.  It happened again at work and an employee of mine insisted I go to the hospital where nothing was diagnosed.

It wasn't until my right foot would never cooperate that I began to worry and seek medical attention.  None could find a thing wrong.  Then the horrid backache that felt like a raw open nerve.  With that I began seeking specialists after specialist.

May I suggest, asking that new neuro for a 3t of your spine.  A l.5t usually doesn't show spinal lesions well.  I have but one small lesion on my brain.  My first neuro chalked it up to age.  He had a spinal MRI done on a 1.5 t and nothing showed.  I sat three and one half years under the idiot losing a great deal of my body strength.  Please make sure you are using a high powered enough machine to see lesions on the spine.  JMO
Helpful - 0
1548924 tn?1296255044
Thank you both so much for your input!  I'm goin' to a new, non-quack, Dr. on Jan. 18th and hopefully she'll get the ball rolling to do the spinal MRI and see what goes.
Thanks again!
take care and be blessed,
Helpful - 0
572651 tn?1530999357
We have a very good Health Page on this very topic - check it out at


Good luck with this.
Helpful - 0
Have an Answer?

You are reading content posted in the Multiple Sclerosis Community

Top Neurology Answerers
987762 tn?1331027953
5265383 tn?1483808356
1756321 tn?1547095325
Queensland, Australia
1780921 tn?1499301793
Queen Creek, AZ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Find out how beta-blocker eye drops show promising results for acute migraine relief.
In this special Missouri Medicine report, doctors examine advances in diagnosis and treatment of this devastating and costly neurodegenerative disease.
Here are 12 simple – and fun! – ways to boost your brainpower.
Discover some of the causes of dizziness and how to treat it.
Discover the common causes of headaches and how to treat headache pain.
Two of the largest studies on Alzheimer’s have yielded new clues about the disease