I was suppose to be in a study at NIHS for cQ10 for PPMS 6 years ago. I do not know how the study came out. There is probably something to it.
To be honest, this product and that website to not pass my sniff test. There are too many red flags, from the lack of scientific studies on the product to the lack of peer review on the site you mentioned. In the world of drug treatments, anecdotes don't count. I'm glad you feel it's doing something for you, but absent evidence that I couldn't find, I'm not lightening my wallet.
Mentions on various websites found via google are cut-and-paste press releases, not 'articles'. The phrase "a dozen years ago" pops up in internet mentions from 2012, 2013, 2014, 2015, 2016 in word-for-word form. It's a sales pitch.
I can not find a legitimate study on PubMed relating to MitoQ. If you have one, please link to it as I would be curious to read it. Accidental discoveries become innovations when they can be replicated and stand up to scrutiny. This just feels like another product that slipped through the dangerous supplement loophole in the FDA.
You might be interested in this article, Andipw3 -- not sure it will link, but if not, search "Is multiple sclerosis a mitochondrial disease?" Peizhong
My naturopathic doctor agrees with the mitochondrial link to ms; for the moment I am supplementing with a few things. It might help. It might be a colossal waste of money :P.
Thank you! I'll look into it.. I think there's something to mitochondrial connection.. I agree.. We all have to be careful. I don't think the FDA approves any vitamin- supplements..? Isn't that true?
Hi there.. Check out ( Google) mitochondrial dis function and neurological diseases.. There's great info out there.. By the way Q-10 has been used for Parkinson's ( high doses). And it's not so much mito -Q specifically as opposed to Q-10 - ubiqionol. I think it's best to study mitochondrial disfunction in neurological diseases and you'll see more about Q-10 . Mito Q is just a more absorbable form of it. Let me know what you think!
I remember you mentioning that. I'd love for you to look into ubiquinol.. It's more absorbable than coq10. Less expensive than the mito-q" . Coq10 has been proven safe and as I mentioned, used in high doses to treat Parkinson's and I believe Alzheimer's. As far as ms goes I think it's worth trying to see if it helps with fatigue, and energy. I've also noticed I'm much more " clear headed". Not as foggy as I've been.
Research what you can and of course talk with your doctor.
By the way, I'm not sure how " best answer" came up?!?? Lol! I must have hit something???
It's the lack of information regarding the 'brand name' formulation that raises my antennae. Whether or not Co-enzyme Q10 as either the ubiquinol or ubiquinone molecule is useful in certain conditions is another discussion. It's the sales pitch and claims of this particular, apparently untested formulation that has me very skeptical.
It appears one formulation HAS been approved by the FDA as an orphan drug for very rare disorders such as coenzyme Q-10 deficiency, as well as conditions resulting in mitochondrial deficiencies. Most of the published data seems to be in relation to heart disease, and the claims of benefit seem equivocal.
The good news is it doesn't seem to be harmful. I'm just not seeing where it's beneficial either. And good quality info on the specific version you mention seems non-existant.
Gotchya! Ok.. Well Yes, I'm thinking that trying the more absorbable q-10 is a safe experiment with regards to energy . It will benefit on the cellular level.. Particularly the mitochondria found in all cells. So I think there may be multi benefits. I have a feeling this mitochondria target is going to be a new buzz word with MS. In a good way. I'm certain there is no money for the pharma companies to make off it .. So it's realky a question of if anyone is interested in additional " help" in a more natural way. I hope some of you give it a shot. Fatigue is one of the awful , sometimes daily, struggles for so many of us. All I can say is I feel better. I don't know what else to contribute it to. I thought about going off it and see. But I don't want to take the risk! I've been much more " myself" with it.
Also!!!! My MRI came back stable . So I can stay in my copaxone. Yay.
Actually, the main study I was able to find was co-sponsored by the advocacy group "International Coenzyme Q10 Association" and PharmaNord, a pharmaceutical company. The trope of pharma not being interested because it's not patentable doesn't hold true here. In fact, sales of CoQ10 reached almost a billion dollars in 2008. So, there's plenty of profit there, mixed with almost no regulation of the claims made. I find that a toxic cocktail.
Again, I couldn't find any mention of it causing harm, but no evidence of benefit. I get very protective of our community (the wider MS-having community) when great claims are made. They require great evidence. Corrie is correct that there are many fronts on which we can fight back, but critical thinking is a heck of a weapon. It's the one I prize most.
Very interesting! I have an appointment later today with my naturopathic doctor and will ask him for his take on this. I am dealing with CRAZY fatigue and weakness to the point where I am barely functioning, I can't continue like this.
Hi Karen.. Remember, it doesn't have to be " mito-Q".. Just a more penetrative form of Q-10.. Or ubiquinol. Regular q10 has not shown to absorb as well. Again.. If it's not dangerous.. And affordable. May at least try it. For fatigue. Im still going strong. I just don't know what else it can be. Will be interesting however when the heat arrives. That is quite the trigger.
I'm wondering when the main study was done on Q-10. The ubiquinol format I think is fairly recent. In any event.. If it's safe.. Reasonably priced.. Data or not I can certainly attest to how I feel.
Hi Karen.. In looking at calm g it doesn't really compare to the amount of Q-10 that I'm speaking of which is the reduced form of Q-10. Your doc is correct in that Q-10 is helpful to the heart.. As the heart uses the most energy. The brain is right behind it with energy production.. So what's being looked at is now.. How this is helpful to those who have neurological issues. I'm certain we'll be seeing more on this as time goes on. First you need to understand mitochondria. Then learn how Q -10 functions with the mitochondria. Then maybe it makes more sense. Again... I'm not advocating a cure, I'm not saying what I'm taking is going to help everyone as there's no such thing. It's more of trial and error within safety zones. My fatigue issues have improved greatly. Not 100 percent. But I'm getting through the day. With much more energy and efficiency. For now anyway.. Time will tell!! Good luck!!