Aa
Aa
A
A
A
Close
Avatar universal

How Long does it take for Baclofen to start working?

Hello everyone.
I took my first does of Bqclofen last night.  My legs started burning.
I don't know if that had to do with the drug or my funky symptoms.
Either way, this mornng i am still having spasms and was wondering how long it usually takes for it to start working and what is the "usual" does who have a lot of speciosity.

I know it's a tough question because we are all different but I figured we are generally in the same boat.
I am going to take 10mg every night for five days and if it doesn't work, I will take 20mg at night for five days.
If that doesnt work, I will take 20mg at night and 10mg in the am.  If that does not work then i am [email protected]&$&@&d!
Sorry for the swear in cognito.

I see the doc on July 11th anyway.
Thanks again, all you kings and queens of ms land!

Kerri
6 Responses
1453990 tn?1329231426
As I posted the other day, it typically starts working within 60 min of ingestion and has a serum half life of 6 hours.  My doctor felt there was no need to titrated up over a week.  He had me try 10 mg  at bedtime and if that didn't work, move to 20 mg the next night.  

There is a difference if you are using Baclofen 3 times a day or as needed.  Since I use it as needed, the serum level doesn't ramp up like someone dosing every 8 hours.

Talk with you doctor, because there a few different dosing options with Baclofen.

Bob
739070 tn?1338603402
Hi Kerri,

Below is a link to my favorite drug information site. They usually give you  a "normal" dosing schedule but please read this as information only and only act upon what your physician tells you.

http://www.rxlist.com/kemstro-drug.htm

Hope this helps,
Ren
572651 tn?1530999357
My neuro had me titrate the dosage - I am now taking 60-80 mg a day (20mg, 3-4 times as I feel it is needed).  

That is a great link from Ren for understanding this drug.  

I hope you find a good balance and it begins to work for you.
best. Lulu
338416 tn?1420045702
I found that I could 'feel' the one pill.  After a week, I started to have spasms again, so went up to two pills, and so on.  I stopped titrating when I reached a dosage that would control my spasms.  I still have mid-day spasms, but not all the time, so I take a flexaril when needed.

So yes, you're doing exactly right - keep titrating up until you reach a dosage that controls your symptoms.  I would see if a Flexaril will help in the meantime.

If you're experiencing burning, is that from the spasms?  Or is that a paresthesia?
Avatar universal
I have tremors caused from a headinjury. the doc, put me on 10 mg of baclofen  and it worked alittle, they are little round pills. so he put me on 20mg but wants me too take 2 of the 10 mg till I run out of the meds and then take 20 mg of which are ob long. anyway, the two 10mg works wonderful. the tremors almost stop. and when i take the 20 mg it seems not too work at all!! what should I do? I thought that if the pharmacist gave me the 20 mg round pills that would work. should I ask him too give me the round one. or ask my dr. for another pill or what?  I am in desperate need. the treamors are just as bad as they were before I started taking them.
Avatar universal
Hi. You have commented on an old post - so it may not be seen. Try going back to the main forum page and chose the Post a Question - if you use your original title for your post jensequitur is sure to see it.

Good luck to you.
Have an Answer?

You are reading content posted in the Multiple Sclerosis Community

Top Neurology Answerers
987762 tn?1331027953
Australia
5265383 tn?1483808356
ON
1756321 tn?1547095325
Queensland, Australia
1780921 tn?1499301793
Queen Creek, AZ
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Find out how beta-blocker eye drops show promising results for acute migraine relief.
In this special Missouri Medicine report, doctors examine advances in diagnosis and treatment of this devastating and costly neurodegenerative disease.
Here are 12 simple – and fun! – ways to boost your brainpower.
Discover some of the causes of dizziness and how to treat it.
Discover the common causes of headaches and how to treat headache pain.
Two of the largest studies on Alzheimer’s have yielded new clues about the disease