Aa
Link between low uric acid leves & MS
Does anyone have any real info on the link between low uric acid levels and MS? My husband came across something online a few months ago and told me I should buy some inosine (a precursor to UA) and give it a try. I just got my bloodwork back from the life insurance policy today, and the only abnormal level was a low uric acid??
I guess I might as well go buy some inosine, the thousands of dollars we've spent on tests and doctors has pretty much gotten me NOWHERE!
If anyone knows that this info is not accurate, I would like to hear from them. I just got off work and don't have the energy to look it all up right now.
Stacey
I guess I might as well go buy some inosine, the thousands of dollars we've spent on tests and doctors has pretty much gotten me NOWHERE!
If anyone knows that this info is not accurate, I would like to hear from them. I just got off work and don't have the energy to look it all up right now.
Stacey
Hi Stacey
My D.O. left a note for me , to look into this before our next appt. Low uric acid / MS ..tx. inosine .
I found many articles including the one you sited. It seems there is a connection some how.
Have you continued with the inosine and have you seen any benefit .. ? I know you got a Lyme dx. right ? but not convinced all sx. fit.. sorry if my memory is not correct.
Does any one have any more info ?
Jo
My D.O. left a note for me , to look into this before our next appt. Low uric acid / MS ..tx. inosine .
I found many articles including the one you sited. It seems there is a connection some how.
Have you continued with the inosine and have you seen any benefit .. ? I know you got a Lyme dx. right ? but not convinced all sx. fit.. sorry if my memory is not correct.
Does any one have any more info ?
Jo
Low uric acid
Multiple sclerosis
Lower serum values of uric acid have been associated with Multiple Sclerosis.[16] Multiple sclerosis (MS) patients have been found to have serum levels ~194µmol/L, with patients in relapse averaging ~160µmol/L and patients in remission averaging ~230µmol/L. Serum uric acid in healthy controls was ~290µmol/L.[17] (1mg/dL=59.48 µmol/L)[18]
A 1998 study completed a statistical analysis of 20 million patient records, comparing serum uric acid values in patients with gout and patients with multiple sclerosis. Almost no overlap between the groups was found.[19]
Uric acid has been successfully used in the treatment and prevention of the animal (murine) model of MS. A 2006 study found that elevation of serum uric acid values in multiple sclerosis patients, by oral supplementation with inosine, resulted in lower relapse rates, and no adverse effects.[20]
I KNOW THIS ALL SOUNDS KINDA CRAZY...BUT I HAVE ORDERED SOME INOSINE AND WILL BE GIVING IT A TRY!! LOL (my level was 202)
Stacey
Multiple sclerosis
Lower serum values of uric acid have been associated with Multiple Sclerosis.[16] Multiple sclerosis (MS) patients have been found to have serum levels ~194µmol/L, with patients in relapse averaging ~160µmol/L and patients in remission averaging ~230µmol/L. Serum uric acid in healthy controls was ~290µmol/L.[17] (1mg/dL=59.48 µmol/L)[18]
A 1998 study completed a statistical analysis of 20 million patient records, comparing serum uric acid values in patients with gout and patients with multiple sclerosis. Almost no overlap between the groups was found.[19]
Uric acid has been successfully used in the treatment and prevention of the animal (murine) model of MS. A 2006 study found that elevation of serum uric acid values in multiple sclerosis patients, by oral supplementation with inosine, resulted in lower relapse rates, and no adverse effects.[20]
I KNOW THIS ALL SOUNDS KINDA CRAZY...BUT I HAVE ORDERED SOME INOSINE AND WILL BE GIVING IT A TRY!! LOL (my level was 202)
Stacey
Have an Answer?
You are reading content posted in the Multiple Sclerosis Community
Top Neurology Answerers
Australia
ON
Queensland, Australia
Queen Creek, AZ
Find out how beta-blocker eye drops show promising results for acute migraine relief.
In this special Missouri Medicine report, doctors examine advances in diagnosis and treatment of this devastating and costly neurodegenerative disease.
Here are 12 simple – and fun! – ways to boost your brainpower.
Discover some of the causes of dizziness and how to treat it.
Discover the common causes of headaches and how to treat headache pain.
Two of the largest studies on Alzheimer’s have yielded new clues about the disease
