Lisinopril & MS?

[Inallev]

Would anyone here know, how long it would take lisinopril, a BP medication to remylinate the brain?

I am referring to the study. Done at Stanford, where the rats with MS were given Lisinopril.

Many tx,

nancy

[SarahL2491]

think we are years from a human use; look at how long Lemtrada fought to get the FDA approval!  Interesting though, my husband, with NO MS takes that drug.

[immisceo]

If it's only been done using the animal model of MS, there wouldn't yet be a determination as to the safety, dosage, or replicability of such a course for humans. A pilot study would be done first typically to determine if it even would demyelinate a human brain. It would be a highly unethical doctor to prescribe an ACE inhibitor off-label for a non blood pressure issue at this very early stage of the research.

There is a company who has obtained an Investigational New Drug licence from the FDA for testing purposes, but any movement towards the market is likely years off.

(the following link is to a press release, so reader beware)
http://www.prnewswire.com/news-releases/fda-clears-ind-for-first-clinical-trial-protocol-developed-using-crowdsourcing-183922651.html