Every single symptom you describe can be caused by Borreliosis. I think it is worthwhile for you to also look into Lyme Disease. The European species of Borrelia causes more neurological symptoms than what is seen in the US. The knee pain you describe is very common in children. Your current symptoms are consistent with late stage disease. I have late stage Lyme and my symptoms also mimiced MS.
Ask your doctor for blood tests for Lyme. Usualy, labs do a two tier testing process where they run a screening test first, and then if it's positive, they run a Western Blot. Unfortunately, the screening test is much less accurate than originally believed. Ask your doctor to specifically request the Western Blot. Unfortunately, it can also be false negative also. You are welcome to come to the Lyme forum to learn more to see if it is a possibility for you.
There is more info that might be helpful for you on lymeneteurope.org
You might also watch the documentary "Under Our Skin."
Stacy,
Please please see a rheumatologist. I was 25 when I ended up in a wheel chair unable to walk and in excruciating pain. The only issue I had as a child was a tendancy to dislocate. I was eventually diagnosed with MCTD. I am now working full time, and doing yoga 2x a day.
What you describe is eerily similar to what all I went through. The doctors initially thought it was MS, then DDD, prophyria, lupus, MG, and about 100 other things. after an excruciating process, I ended up with a rheumy who had read about a rare subtype of MCTD, and sent blood to the single lab in the US that can test for it.
It took me about a year to get back to "normal", it was hard and painful, but so worth it.
hi thank you for your comment that is a real eye opener ive never actually heard of that but there are a couple of things in that list of symptoms that i have but i didnt think were relevant i am definatly going to mention it to a doctor
Do you have your thyroid results? Deranged means "to upset the normal condition or functioning of" so not a good sign when it comes to your thyroid gland. In one study, 40% (89 of the 219 patients) with unexplained chronic fatigue over 1 year had proven autoimmune thyroid disease (diagnosed by FNA biopsy) regardless of baseline TSH levels. 50 had a TSH level within the normal reference range and 37 where outside the reference range.
Also, check vitamin B12 levels and make sure your results are at the upper end of the reference range since ranges are far too low in most countries. Vitamin D, iron and vitamin B12 are the three most commonly mentioned deficiency states with hypothyroidism. Vitamin B12 deficiency is one of the MS mimics.
However, considering your extreme muscle weakness, Myasthenia Gravis (MG), a rare autoimmune disease of the muscles which results in muscle weakness and fatigue, needs to be ruled out. Myasthenia gravis is associated with various autoimmune diseases including: thyroid diseases, including autoimmune thyroid diseases Hashimoto's thyroiditis and Graves' disease, diabetes mellitus type 1, rheumatoid arthritis, Lupus, and demyelinating CNS (central nervous system) diseases.
An article from a MG sufferer who was misdiagnosed for many years...
"What the Heck is Myasthenia Gravis?" by Kerri Sweeris - Yahoo! Contributor Network...
"June is Myasthenia Gravis (MG) Awareness Month. I am starting now to get the word out, and will be posting a series of articles on MG and how it effects my life.
The kind of MG that I have, MuSK+, effects about 7 people out of a million. (Okay so I'm not one in a million...) Some of the symptoms are:
"Some of the symptoms are:
*Double vision
*Drooping or even closing of the eyelids from weakness
*Swallowing difficulties, frequent choking
*Weakness of the intercostal and diaphragmatic muscles, which means lying on the back is nearly impossible (if you want to breathe, anyway)
*Hoarseness and changes in voice
*Weakness or paralysis that worsens as the day progresses
*Facial paralysis (all of the muscles in my face were so slack everyone at work kept asking me why I was so angry...I just couldn't smile because none of the muscles worked anymore)
*Temporarily absent breathing (like you breathe out and forget to breathe in again)
*Sustained difficulty breathing
*Drooping head (as neck muscles are too weak to hold it up...this is awful. My head sometimes just kind of flops over.)
*Poor posture
*Difficulty climbing stairs
*Difficulty lifting objects
*Difficulty talking (slurring words, inability to enunciate clearly, especially after talking a while, or eating something cold. I actually have a card in my purse that says, "I'm not drunk, I have Myasthenia Gravis!")
*Difficulty producing the right words when needed
*Difficulty chewing
*Fatigue
*Overall, generalized weakness
*Weak muscle tone
*Muscle pain (due to atrophy from not using muscles enough)
*Frequent clumsiness and poor balance
*Frequent dropping of items due to weak grip (I've broken many a glass! And my husband STILL makes me do dishes!)
I can honestly say I have or have had all of the symptoms listed above. It is not fun. A crisis situation (which means getting to a hospital ASAP) can occur at any time. A person with MG may be fine when they get up in the morning, and collapse for "no" reason in the afternoon. I have actually fallen off the toilet because my leg muscles just gave out. You don't really think that you're using a lot of muscle by simply sitting on the toilet, but you'd be surprised! (You can laugh, it's funny NOW!)
I started having my first symptoms of this wretched disease in July of 1995, 6 months after I had chronically infected tonsils removed. I was 24. That was almost 15 years ago. I was undiagnosed until July of 2003, and went through hell and back in between to find a diagnosis.
Stay tuned for more information in the next article about me and MG."