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What does abnormal T2/FLAIR subcortical deep white matter of both hemispheres mean?

After having a MRI done of my husband's brain/brain-stem w/o contrast, the report says: SIGNIFICANT ABNORMALITY, ATTN NEEDED. 1. Nonspecific foci of abnormal T2/FLAIR signal subcortical deep white matter of both cerebral hemispheres. Differential considerations include gliosis and myelin loss. 2. No mass effect, obstructive hydrocephalus or intracranial hemorrhage. 3. paranasal sinus inflammatory changes. The septum pellucidum is midline. Bihemispheric subcortical and deep white matter predominantly periatrial abnormal T2/FLAIR signal is nonspecific.
His history for the scan was severe left side of brain headaches, facial twitching on the left side, left hand twitching, loss of balance, noise emanating from deep in brain, heart palpitations and racing heart beat, elevated blood pressure and dull persistent pain on right side over liver and memory loss.
These symptoms appeared after being injected with 3 different neuroleptics and have continued to be troublesome.  Do I need to be worried when this report says SIGNIFICANT ABNORMALITY, ATTENTION NEEDED?
What does all of this mean?      
1 Responses
5265383 tn?1483808356
I find it intriguing that they emphasized a significant abnormality, while also calling the lesions non-specific?  Very unusual wording for a radiologist to use -- generally they say something along the lines of "suggest further imaging`` if there is an area in question.   I'm sorry, only your neurologist will be able to unravel the meaning of the white matter lesions found.

Usually the differential for non-specific lesions also includes ischaemic changes and migraine, as well as demyelination.  I`ve never had gliosis mentioned as a possible cause on mine. The radiologist, in this report, has not mentioned any typical areas of concern for multiple sclerosis (periventricular, brainstem, juxtacortical lesions) -- sounds lilke subcortical lesions only.

I've had neurologists frustrated by a radiologist "over reading" the  mr imaging and I wonder if this is the case here?  Honestly, in the age of patients receiving imaging results online prior to seeing a neurologist, your radiologist needs some patient sensitivity training!

Some of the symptoms your husband is experiencing could be because of a neurological issue, however with elevated blood pressure and heart rate issues it is more likely to be related to ischaemic change .. in my completely non-doctor opinion, so please take with a large grain of salt.

Hoping you can see the doctor shortly to get a full explanation for this mri!  What a disconcerting warning :(.
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