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Avatar universal

how likely is ms in in these circumstances please?

Hi - posted once or twice before on here.
Difficult question I know, but how likely would MS of some kind be with the following tests and symptoms:
End of last year - clear mri on brain. then follow-up mri on neck and spine clear.
Last month - clear EP's (visual, somatosensory lower limbs, motor lower limbs).
Neuro exam, repeated in January, was relatively normal, except for fasiculations noted.
Also had EMG and nerve conduction studies in January (not testing for MS) - again normal.
Still getting fairly constant twitches on calves and eyelids and feel like they're happening on back and arms.  Some pain on legs - particularly burning on left thigh, occasional balance issues - much less so now, occasional numbness on both cheeks.  Problems started in September with these issues plus others (including receding gums).
Am a male aged 45.
Many thanks.
2 Responses
Avatar universal
Considering what you've written, the likelihood of your having MS approaches zero. Twitches (fasciculations) are rarely a part of MS unless associated with some other problem in the same muscles. MS symptoms do not occur symmetrically on each side (i.e., both calves, both eyes) unless there are lesions exactly the same on each side, and this rarely happens. And so on.

The EMG/NCS testing was to find evidence of a peripheral nervous system problem, which cannot be MS.

I think you really need to talk about all of this with your primary doctor, who I hope knows you and your health history. It may be time to consider whether some other problem is causing what you experience. He or she knows you and we don't. Good luck.

5265383 tn?1483808356
Two ideas when you see your primary doc ... not a bad idea to have your magnesium level checked.  The blood test isn't super helpful (only 1% of the body's magnesium is in the blood and even less than that is in the serum), however low magnesium can cause twitching so it's something to consider.  If the blood test comes back low you are quite deficient.  There is another test called the magnesium load test that is more accurate.

Secondly, there is a condition called benign fasciculation syndrome (BFS) -- could possibly be something like this that is unrelated to any other disease process.

I've had fasciculations and twitching, which muddied the water for my ms diagnosis because they are not ms symptoms.  I did end up having a severe magnesium deficiency -- I haven't had a fasciulation in over a year, and barely twitch at all now that I supplement with magnesium.  However I wouldn't supplement without being tested and under a doctor's supervision.

Agree with Ess above -- these symptoms aren't typical of ms.  Hopefully you and your pcp can hammer out a plan to figure things out :).
Thanks Ess and Aspentoo.
Just got word back from the Neuro on sone bloods he ran - I have positive antibody to voyage gated Potassium channel, whatever that means!
So I need to ge the blood test done again.  Other bloods were normal, except low lymphocyte late last year.
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