I took Cymbalta while on Methadone and had no drug interactions. I was placed on the Cymbalta for my issues with Bi-polar disorder but, had no luck in it helping me. That's just me though. I attend a Methadone clinic here in Cincinnati,Ohio and my doctor there watches us very closely. He had no issue with placing me on the medications together. Best wishes to you and please keep us updated on what happens!
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