The hydrocodone (opiate) portion of Lorcet would take about 24 hours to clear in an adult once that person stops taking the medicine. There are no data for how fast a fetus clears the drug.
In general, if a mother is still taking a short acting opiate within 1 week of birth, the baby is closely observed for possible signs of opiate withdrawal. If the medicine has a very long duration of action (e.g. methadone), then the mother needs to stop the medication earlier to avoid withdrawal effects in the newborn baby.
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