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Constant Headache with Pressure above the Right Eye

My husband has been suffering from headaches that really never go away and pressure above his right eye which never goes for about 2 year. His neurologist diagnosed him with hemi crania continua (lamens terms: one nasty non-stop heahache) and prescibed indomethicin, says they have had good results in treating hemi crania continua. However, he was hospitalized in February with a colonic fistule and during his stay in the hospital the headaches and pressure disappeared, due largely I am sure to the pain medication he was receiving through his IV.  About two weeks after being released from the hospital the headaches and pressure were back with a vengence and now no amount of indomethicin gives him relief. Please help us determine what the cause is and how to treat it or better, cure it.  He also suffers from depression for which he takes Wellbutrin and has taken for about 10 years, he takes Sinamet for Restless Leg Syndrome and Klonopin for Centralized Sleep Apnea, he has also taken these medications for at least 10 years as well.
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