If your levels for B6 are still high, you should get a blood test for ALP - alkaline phosphatase, and look into hypophosphatasia. High B6 and low ALP are the markers for this disorder.
My level is 890nmol/L. How do I get my B6 level down? I stopped taking supplements with b6 and reduced the b6 high food I eat but my b6 levels continue to get worse not better. My body is in pain all the time and my brain doesn't work any more, I get hot when it is cold and have bad headaches every week and get body tremors. I am sick of relying on high doses of pain killers to help me deal with the pain. I tried relaxation and am trying to exercise but nothing seems to help.
Hi. I don't know if you will get this but felt I should try. In doing my own research on various deficiencies I came across some information suggesting tests on your different glands is thyroid, adrenal, etc. Good luck and I hope you've found your answers by now and don't need this.
Hi
Most of my symptoms have gone, although they have become a weak spot in times of stress or being tired. In order words I will use the symptoms (twitching muscles, tinnitus, sore muscles, sure throat or GI issues) as signal to tune down or change gears.
In general I am doing much better than I used to be over the last 2 years. Only vitamin D shortage could be linked to my health issues – but could not explain all. Vitamin B6 levels appeared to be less of an issue.
Due to the lack of a clear-cut cause, my issues could be a somatic manifestation of a burn-out or long term stress. Perhaps I have been building up stress not just through physical exhaustion (travelling, long hours at work, little unwinding etc) but also a result of my mental state, i.e. my sensitivity to build up stress. Stress may eventually impact your physical state including vitamin needs etc.
In previous posts I already summed my “survival/recovery” strategy. In the last months I have started to focus on the mental part as well. For me it helped. In random order I apply more or less the following:
• Sufficient sleep, relaxation (books, fun stuff, etc) and when needed sometimes some meditation (e.g. mindfulness)
• Sufficient exercising with a focus on strength, balance and cardio. Sufficient fresh air.
• Healthy food, water and certain supplements (such as all fat soluble vitamins including D (don’t overdose), zinc, magnesium, B complex (be careful for the vitamin B6 dose)). Less coffee, chocolate, fast food etc
• More structured days (eating, agenda, sports etc) - and differentiate private and work life. I had it mixed up.
• Accept your limitations - this was and is a tough one for me. But key!
• Sufficient time for family and hobby's. Socialize. On your own, things may become or look worse.
• Introspection - learn about your own personality and its pitfalls. Counseling may help here. More spiritual time.
• Do (action) instead of think.
• Most important: listen to my body. The signals say something. Often they say: relax and continue tomorrow.
• I had to overcome my anxiety, i.e. my fear of not knowing what I had or could have. I did this through applying NLP myself. Also I stopped browsing the internet for answers. There are a lot of worrying things on the web which usually do not apply for you at all.
It is very difficult to advise others on health issues and blood values. E.g. there are numerous reasons why vitamins could be off: Physical/mental exhaustion could be one reason. Little to no sun, combined with low Vitamin D intake and/or unhealthy eating habits and/or GI issues could affect the Vitamin D status. Vitamin B6 is often an enigma, unfortunately. I have not come across the golden bullet to reduce vitamine B6 levels. Also realize that blood values don’t always mean something – what is good for you could be an issue for another. My higher Vitamin B6 values, after all, could not be related to anything. Probably I am just above average. I do advise to have blood values tested a second time after 1 or 2 months, in case a value is off.
General advice:
• Be aware of your physical symptoms – listen to it. Often your body is requesting rest or another change. Needless to say for people who visit this site
• If you don’t trust your symptoms consult a GP or another doctor/person who may help you
• If there is no obvious physical cause, consider mental exhaustion or stress (in whatever form).
• Consider “YOUR” life strategy re health, sleep, structure, food habits, exercising etc. Sometimes you don’t need a pill, but just a life style change, which could feel as a very bitter pill
.
Wish you all good health !
RideWa
Hi
Most of my symptoms have gone by now, although they have become a weak spot in times of stress or being tired. In order words I will use the symptoms (twitching muscles, tinnitus, sore muscles, sure throat or GI issues) as signal to tune down or change gears.
In general I am doing much better than I used to be over the last 2 years. Only vitamin D shortage could be linked to my health issues – but could not explain all. Vitamin B6 levels appeared to be less of an issue.
Due to the lack of a clear-cut cause, my issues could be a somatic manifestation of a burn-out or long term stress. Perhaps I have been building up stress not just through physical exhaustion (travelling, long hours at work, little unwinding etc) but also a result of my mental state, i.e. my sensitivity to build up stress. Stress may eventually impact your physical state including vitamin needs etc.
In previous posts I already summed my “survival/recovery” strategy. In the last months I have started to focus on the mental part as well. For me it helped. In random order I apply more or less the following:
• Sufficient sleep, relaxation (books, fun stuff, etc) and when needed sometimes some meditation (e.g. mindfulness)
• Sufficient exercising with a focus on strength, balance and cardio. Sufficient fresh air.
• Healthy food, water and certain supplements (such as all fat soluble vitamins including D (don’t overdose), zinc, magnesium, B complex (be careful for the vitamin B6 dose)). Less coffee, chocolate, fast food etc
• More structured days (eating, agenda, sports etc) - and differentiate private and work life. I had it mixed up.
• Accept your limitations - this was and is a tough one for me. But key!
• Sufficient time for family and hobby's. Socialize. On your own, things may become or look worse.
• Introspection - learn about your own personality and its pitfalls. Counseling may help here. More spiritual time.
• Do (action) instead of think.
• Most important: listen to my body. The signals say something. Often they say: relax and continue tomorrow.
• I had to overcome my anxiety, i.e. my fear of not knowing what I had or could have. I did this through applying NLP myself. Also I stopped browsing the internet for answers. There are a lot of worrying things on the web which usually do not apply for you at all.
It is very difficult to advise others on health issues and blood values. E.g. there are numerous reasons why vitamins could be off: Physical/mental exhaustion could be one reason. Little to no sun, combined with low Vitamin D intake and/or unhealthy eating habits and/or GI issues could affect the Vitamin D status. Vitamin B6 is often an enigma, unfortunately. I have not come across the golden bullet to reduce vitamine B6 levels. Also realize that blood values don’t always mean something – what is good for you could be an issue for another. My higher Vitamin B6 values, after all, could not be related to anything. Probably I am just above average. I do advise to have blood values tested a second time after 1 or 2 months, in case a value is off.
General advice:
• Be aware of your physical symptoms – listen to it. Often your body is requesting rest or another change. Needless to say for people who visit this site
• If you don’t trust your symptoms consult a GP or another doctor/person who may help you
• If there is no obvious physical cause, consider mental exhaustion or stress (in whatever form).
• Consider “YOUR” life strategy re health, sleep, structure, food habits, exercising etc. Sometimes you don’t need a pill, but just a life style change, which could feel as a very bitter pill
.
Wish you all good health !
RideWa
Same deal for me, TestSri: toxic B6 and B12. My D, however, is fine. I don't supplement at all, so I have no idea how to reduce my Bs when they're intrinsic in every food group.
I've been suffering with peripheral neuropathy for three years; my neurologist says it will only get worse unless I figure out its cause. Sigh. I can't find my way out of this tunnel.
What's your current experience?
Hi Ridewa,
Hope you are doing well. My case is very similar to yours(Low is vitamin D(14) and high in B6(104), B12(375)) . Did you overcome all of your symptoms? Please share your thoughts.
Thanks
Hi,
I am a 38 year-old woman with similar labs and labs as you all. High B6, low D, low alkaline phosphatase. I was a healthy person until I got run down as a sleep-deprived, nursing mom. I developed shingles followed later in the year by intractable nerve pain in my feet and legs. The nerve pain is now in my arms and legs (diagnosed as small fiber peripheral neuropathy). I also have bone pain in my arms. I don't have other symptoms of hypophosphtasia. I'm trying a gluten free diet because there can be weird neurological issues. I too am trying to figure out how to lower B6 when my intake is already low. I am hoping to gwt some answers from my 23andme test. There can be issues with MTHFR and CBS genes that affect B6 metabolism. I will report any revelations. I'm sad and glad that others share such a similar experience. Good luck on your journeys to health!
p.s. my neurologist also said it maybe out of your blood but not your cells and tissues....so the blood level is not a good indication of clearance...she told me months to years on recovery and I have talked to a few from up to7 years out....most say keep going it gets better but some still have symptoms...best of luck
After taking b complex 50 mg for 14 days I became toxic and have had all the pain, pins needles tinnitus, etc....been tested for every disease known to man and nothing..MRI clean, etc....B6 is pure poison and it is a slow recovery....I have good days, and then like today, it all comes back....I even lost hair, and my thyroid has become hypo...wish I had never taken a vitamin in my life...I was just fine before that!
I too have low vitamin D (~30) and just got my results for vitamin B's. B6 was high at 146.9nmol/L (range of 20-125 is considered normal). B12 was also low at 0.11nmol/L. For about a year now I have been experiencing mind fog.. its like a feeling of detachment from my surroundings. If you read about depersonalization, that sort of describes it. I know low vitamin D can cause this in people who live in colder climates from lack of sunlight/working indoors. I have been tested for EVERYTHING trying to rule out what is causing me to feel this way. It started after I went on a vacation to St Maarten and drank for a week straight. Some days are worse than others, but I never feel 100%. Ive been tested for STDs, Lyme, anemia, vitamin deficiencies, I had an MRI which showed a 1cm cyst on my pineal gland (which the gland itself is only 0.5cm) but the doctors keep telling patients with these cysts that theyre asymptomatic and benign. We all think otherwise.. but anyways, based on some of my symptoms (dizziness, ringing in my ears, mind fog, sometimes lack of coordination & balance, light headedness especially when I stand up) someone mentioned to look into different types of autonomic disorders. I am convinced I have POTS (postural orthostatic tachycardia syndrome) which is symptoms due to an underlying problem.. could it be low vitamin B12, Vitamin D, yet I have elevated B6? Could it be a combination? Could it be the cyst growing in my brain? Could I have low blood pressure so not enough blood is getting to my head and is causing me to have POTS symptoms? I started taking a B complex vitamin (**prior to my last blood tests) and 5000IU of vitamin D, along with daily vitamins, fish oil, and calcium. I also bought a blood pressure monitor and have started making sure I drink a minimum of 2L of water everyday. There are times during the day that i do feel ok.. I try not to evaluate how I am feeling because I think it is stressing me out.. for a YEAR I have been researching and thinking I had lyme, thinking something was seriously wrong, maybe brain damage.. not sure. But I have noticed my blood pressure (I bought a monitor) has been higher with me drinking more water and that I do feel better than I have in the last year.
It is October 2013 and since September 2013 I’ve started to pick up some work again. I had been out since March of 2013. After all, the elevated vitamin B6 seem not to be related to anything obvious. Moreover, the levels had normalized relatively soon after I posted my first message on Medhelp. It is more likely that I have suffered a severe vitamin D shortage, affecting my overall physical condition but especially the neuromuscular performance. D shortage resembles to some degree vitamin B6 toxicity. Whether the vitamin D shortage is the cause of all or a result of something else, probably cannot be determined anymore. Potentially other factors may have affected my health as well, such as an incredible high work load for many years under quite energy absorbing circumstances.
Anyway, I hope my recovery continuous as it does now – I start to feel energy flowing again in my veins. This time I have to listen at all times to the signals my body provides, because it did already before March 2013 but the signals were just denied.
As mentioned above in the previous messages, I had developed some sort of “recovery” strategy, a new life style if you like. I am intending to stick to the scheme:
Adopt healthy food habits (e.g. sufficient vegetables and fruit (eat different colors), mind too high sugar intake, drink sufficient water, minimize caffeine intake, biological food).
Unwind regularly and rest sufficiently (do fun things with family and friends, watch comedy shows, read books, go to bed timely). Put your mind to other things than to your health all the time. Sleep is critical to a good health.
Exercise cardio, strength and balance. Go to a gym, play tennis, go skiing, whatever you like and whatever is possible.
Evaluate your work life and personal life – is it balanced and sustainable ? In my case I was too work focused (perhaps resulting in or at least contributing to my health issues). Working hard is not the issue, but spending too little time with my sons is an issue. They only grow up once. See what’s possible in your situation; not everyone can make (big) changes in order to change their work life balance.
Annual health checks – within your possibilities and needs. For instance I will pursue yearly vitamin checks. Stay the owner of your own health and you may want to consult different types of therapists or doctors in times of need; their input may give you a more holistic view on yourself.
My experience is that if you want to change your life style (food, rest, exercise etc) take it step by step in order to make it sustainable on the longer term.
If there are no further developments (i.e. new health issues), which I hope of course, than this is my last message on this subject. A good health to everybody!
Hi, My B6 is extremely high too. It was found to be HYPOPHOSPHATASIA. If so, Alkaline phosphatase will be low too. This means that you are missing a bit of gene number one which provides this enzyme, hence unable to metabolise phosphates (B6 is pyridoxil 5 phosphate).
Regards Juliana508
Thank you
I think you are right. More specialists have indicated it to me and also my own research leads to that conclusion.
Furthermore one should be careful about reading the blood levels. The levels are often transient and may not reflect the issue in the tissues, as well as normal levels may differ per person. Also i noticed that absolute numbers may differ per lab, oddly enough. Having a second measurement is not a strange thing to do, according to me.
My B6 levels have come down and vitamin D levels are rising. Interestingly, neurologists and neurophysiologists suspect that the low vitamin D levels may have evoked a lot of the issues I suffered and still suffer but to a lower degree. Also they have the experience that usually clinical recovery is lagging from restored levels in the blood. Presumably I am in that phase now.
Most likely multiple factors have impacted my health, but herewith unable to pinpoint the chickens and eggs. Long lasting stress, low vitamin D, irregular life style, my personal physical and neurological profile etc, all may have contributed to a severe imbalance.
I hope the gradual recovery continues, and with sufficient rest and patience hopefully I may embrace a full recovery in the coming time without further serious issues. I'll stick to my 'strategy' of healthy nutrition, exercising etc, since I deeply believe it provides the foundation for recovery and a more balanced life style.
Hi there!
B6 toxicity is unlikely to develop at mildly elevated levels and the symptoms described are unlikely to be related; while a few of these could be related to low vitamin D levels. Other possible causes that may need to be considered include stress. anxiety, metabolic issues. electrolyte imbalance, micronutrient deficiencies, medication side effect, neurological causes, cardiovascular causes, infections/ inflammations etc. I would suggest getting this evaluated by an internist initially and depending on the cause diagnosed/ suspected, it can be managed accordingly or specialist acre may be sought.
Hope this is helpful.
Take care!