I am a 35 y/o WM with progressive symptoms over the last 15 years or so. My symptoms began as myalgias and fatigue and I was diagnosed as fibromyalgia and treated with antidepressants for years. I've always had sleep trouble and GI complaints, so I seemed to accept this diagnosis. Over the last 3 months, I began having generalized numbness and tingling with associated burning and hypersensitivity of my skin, a raw feeling in my mouth and painful teeth. My muscle aches and fatigue continue and seem to get worse with weather change and stress. Because of my new sensory dysesthesisas, I saw a neurologist. He obtained an MRI w/ contrast to R/O MS. The scan was clear. I've also recently had a normal CBC, CMP, ESR, RF, IgG, IgA, cortrysin stimulation test, TSH, Vit B12. My doc changed my meds (Celexa) to Effexor. Over the last 2 weeks, my symptoms have worsend and become unbearable. I'm a physician assistant and a 4th year med student at present. I do not feel that my stress load is difficult at this time. Which is why it is hard to understand my worseing symptoms. I really don't know what to do. I've considered the differential of MS for conditions like amyloidosis, porphyria, sarcoidosis, SLE, sjogrens, lime disease. I have a lime titer pending. I'm not even sure of which doctor to consult or what to do at this point. Do you have any suggestions. Thanks for your help.