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Not sure what to do!

28 year old male, not sure what to do at this point.  I had a CT scan in 12/05' that showed mild chronic sinusitus.  Since this time I have felt it becoming harder to walk, talk, think and see.  I can barely drive, sometimes see spots, cannot think at all, concentrate, eyes feel off, stiff feeling and feel like I'm going through menopause (from what I've heard).  My most recent MRI on 06/07' showed scattered foci of deep white matter T2 hyperintensity which are nonspecific, although somewhat atypical in this age group.  It was noted on a recent CT scan that I had a deviated septum, polyps, chronic sinusitus and a possible mucus pocket.  The neurologist ruled out anything from the white matter stating "I think it's from a previous injury."  ENT said he doesn't believe my deviated septum would cause me to feel like this.  I am at a complete loss.  I have heard everything from Parkinson's, MS, seizures, thyroid, B12 deficiency, anxiety or depression.  I have been on the many medicine's since 2003 for anxiety and depression, but none seem to work and most the time make me feel worse. Sleep Apnea test came back normal, although they said if woken up I would fall right back into the deepest sleep and would wake up almost every 3 minutes. My heart checked after high P02 levels were noted (normal).  I feel like I'm becoming dumber and slower everyday, like my head isn't getting enough oxygen.  I get quite a bit of pain behind my eyes, headaches, feel off balance, weak, sometimes shaky, clumsy during everyday activities.

My homocysteine level came back at 45.4 when it should not have been higher than 11.8.  I had to postpone a gallbladder surgery twice (they put me out) as my P02 levels were sky high.  My B12 was 253 so I took injections for 3 weeks and it went up to 1667.  Here are my results from recent saliva and blood tests.   My eyes barely adjust to light changes and everyday living is becoming almost impossible.

Here are the saliva test results;

fTSH 57 Normal
fT4 0.25 Normal Normal: 0.17-0.42 ng/dl
fT3 0.27 Borderline Low 0.21-0.27
TPO Positive
E2 (Estradiol) 9 Male (20-49 yrs): 1-3 pg/ml, Male (50-85 yrs): 1-5 pg/ml
P1 (Progesterone) 30 Male (adult): 5-95 pg/ml
TTF (Free Testosterone) 34 Male (20-30 yrs): 60-110 pg/ml


7:00-8:00 a.m. 6 Depressed 13-24 nM
11:00-Noon 4 Depressed 5-10 nM
4:00-5:00 p.m. 3 Normal 3-8 nM
11:00-Midnight 5 Elevated 1-4 nM
Cortisol Burden 18 23-42

DHEA 4 Normal 3-10 ng/ml

My morning Cortisol blood test was 19.3 (Range: 4-22 MCG/DL). Antibodies test was negative.

Prior tests:

May 2007:

TSH 0.86 (Range .34-4.82 uIU/mL)
Free T4 0.75 (Range .59-1.31 ng/dL)
T-3, Total 114 (Range 60-181 NG/DL)
Iron 215 (Range 25-156 ug/dL)
%SAT 87.0 (Range 13.0-45.0)
Ferritin 179 (Range 5-244 ng/mL)

October 2005:

TSH .94

May 2006:

TSH 1.20 (Range .35-4.82)
Free T4 .91 (Range .59-1.17)
T4-Total 6.4 (Range 4.5-12.0)
T-3 Uptake 34.6 (Range 25.0-35.0)
Free Thyroxine Index 2.21 (Range 1.12-4.20)

August 2006:

TSH 1.11

Here are my latest lab results.
Results: Reference Range/Units:

Glucose 80
Bun 4 L 6-24 mg/dL
Creatinine 0.8 .6-1.3 mg/dL
Sodium 138 136-145 mmol/L
Potassium 3.8 3.5-5.0 mmol/L
Chloride 105 98-107 mmol/L
CO2 30 21-30 mmol/L
Anion Gap 7 3-12
Calcium 9.3 8.4-10.3 mg/dL
Total Protein 6.8 6.1-8.1 g/dL
Albumin 4.3 3.1-4.7 g/dL
Globulin 2.5 L 2.7-3.9
A/G Ratio 1.7 .8-1.8
Alkaline Phos 112 50-136
ALT/SGPT 52 30-65 U/L
AST/SGOT 23 15-40 U/L
Total BILI 1.2 H .0-1.1 mg/dL
Iron 215 H 25-156 ug/dL
IBCT 247 L 250-450 ug/dL
%SAT 87.0 H 13.0-45.0

Est. Mean BLO 84
TSH 0.86 .34-4.82 uIU/mL
Ferritin 179 5-244 ng/mL
Free T4 0.75 .59-1.31 ng/dL

Doctor said high iron so I donated, % of saturation was at like 80 something, but is now down to 66%.

Medicines I've taken:
I have been on Wellbutrin, Clonezapan, Xanax, Lorazepam, Buspirone, Clomipramine, Seroquel, Lexapro, Zyprexa, Zoloft, Cymbalta, Ativan, Risperdal, Paxil and Paxil CR (I believe that's all....as if that's not a lot). I have also taken Avelox, Ru-Tuss, Prednisone, Hydrocodone, Oxycodone, Lortab, Amoxicillin, Ambien and Lunesta.  Currently I take Prilosec everyday (since 14 for acid reflux disease), 20 mg of Ambien to sleep or Chloral Hydrate to sleep.

I was started on Hydrocortisone and worked up over 17 days to 20 mcg, while taking 5 mcg of Cytomel.  Doctor placed me on Paxil and I had a bad reaction so they stopped everything.

Thanks and sorry for the long post, but I'm trying to lay everything out there hoping someone can help me out.
1 Responses
Avatar universal
Any ideas on what could cause this would be greatly appreciated.  Thanks Again!
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