I am asking this on behalf of my 59 year old grandmother. She has been losing out on alot of her sleep for the past 2 weeks because of the fact that her hand cramps up while she is asleep. The odd thing about this is that the pain does not affect her while she is awake. It is only when she is asleep that it hurts her. She gets up yelling in pain and I come to massage her hand and arm but it seems to only work for a little while. Being so tired she falls back asleep only to be awoken again with searing pain. We have tried using a brace and we also have tried using icy hot patches (which I cut small to place on her wrist) but they do not seem to help at all. Any ideas on a solution to this?