Hi, was diagnosed with TM (idiopathic), took about 3 years. Went to John Hopkins Univ. to see a specialist, i have tried most antispasmatic drugs, baclofen, zanaflex, flexeril, etc... None of these seem to work. I have only the one lesion across both widths of cord. I was told there is no active inflammation, therefore normal treatments like steroids which i tried to no effect, questioned the Dr. about Plasma therapy, was told would not help because of no active inflammation. I am at a loss here, i thought i went to the best hospital, but to my surprise, i was very disappointed in the way i was treated. They have the only TM center that i know of. I have very much difficulty walking, extremely tight calf muscles, very weak legs, i am working out 3 days a week to try and get the strength back. My question is, the new drug that was approved for MS, and other neuro conditions has helped a great deal with most patients, could that be a possibility for patients like me? If i can't get an approved prescription here, i may have to investigate other ways, i guess i want to know would this be a safe medicine for me to try? I am extremely desperate for any help you may have.