So I have inflammation in my mid brain - but my problem is the cause and then I can be made better. The consultant has tried azothiaprine and methotrexate, and now it's cyclophosphomide pulse. He is baffled as well - the tests show no abnormalities except an area of inflammation which isn't enhanced on the MRI. I've had both PET and CT. If the symptoms would go away I could go back to work - I have an essential tremor, double vision and balance problems - like I'm drunk - but I'm not! - Please could someone explain this cos being drunk for an evening is bad enough but for 18 months! Does anyone have any other suggestions - we explored ms at the beginning and I have also had a gastroscopy looking for something. The consultant says that I should be patient and see what the cyclophosphamide does. He doesn't want to do a biopsy cos it's dangerous - bleeds etc. anyway it might not be helpful.