CSF CELL COUNT & DIFFERENTIAL 8/4/2008
CSF - APPEAR CLEAR
CSF - WBC 0
CSF - RBC 1023
CSF - DIFF DIFF NOT INDICATED
CSF CHEMISTRIES
GLU # 40 - 70 69
LACTIC 0.0 - 2.8 2.1
LDH >=0 10
PROTEIN 15.0 - 45.0 25.8
CSF CULTURE MODERATE RED BLOOD CELLS / NO ORGANISMS SEEN
MULTIPLE SCLEROSIS EVAL DATE RECEIVED 8-5-08 DATE REPORTED 8-9-08
IGG SERUM 768 - 1632 1060
IGG CSF 0.0 - 6.0 3.0
ALBUMIN SERUM 3500 - 5200 4160
ALBUMIN CSF 0 - 35 17
ALBUMIN INDEX 0.0 - 9.0 4.1
CFS IGG SYNTHESIS RATE 0.0 - 8.0 1.4
IGG INDEX 0.28 - 0.66 0.69 H
CSF IGG/ALBUMIN RATIO 0.09 - 0.25 0.18
CSF OLIGOCLONAL BANDS NEG POSITIVE A
MYELIN BASIC PROTEIN 0.07 - 4.10 1.38
INTERPRETATION/SPEC CHEM 7
Increased concentrations of IgG in the CSF is an important indicator for MS but may also be associated with increased local production of IgG, or both. Increased IgG production is demonstrated by an increased CSF IgG/Albumin ratio, IgG index and IgG synthesis rate. As compared to the serum, isoelectric focusing/immunofixation reveals 7 IgG bands that are unique to the CSF. This is consistant with intrathecal synthesis of immunoglobulin and is considered to be a positive result for the oligoclonal bands. Oligoclonal bands are present in over 90% of patients with MS but may also be present in CSF from patients with viral or bacterial meningeoencephalitis, SSPE, neurosyphilis, Guillian-Barre syndrome, and meningeal carcinomatosis.
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