Hi, Thank you for your question. Your thigh vibration symptoms could be related to pinched nerve in spine, diabetes, thyroid dysfunction, Vitamin B complex deficiency, neurological disorder or if you are any vibration jobs (like drilling etc). Nerve studies and nerve test may be helpful to further evaluate the condition. I would recommend evaluating the possibilities here with the help of a doctor. Further referral to a neurologist or endocrinologist may be required to assess the condition. Hope this information proves helpful to you.