B6 toxicity

[gkcasey]

One of my clients has a level of 3000?  The previous test was in the order of 2500?  

I know about general toxicity issues with B6 but is there any research on levels such as these.  She displays most of the known symptoms and so does her daughter.  Genetic causes could be a question but I can't find any relevant research.  Any ideas or pointers please.

[Renee Radenberg]

Were they taking the large doses of vitamin B6 supplement to help with relief of PMS, Carpal Tunnel Syndrome, asthma, or heart disease which research has showed vitamin B6 does not have any significant effect on the named above.  Vitamin B6 toxicity causes temporary neurological symptoms, which, according to the literature, usually take up to 6 months for it to resolve itself for majority of people. There are some people who do have permanent damage. It is recommended not to take any supplement of vitamin B6 and try not to eat large amounts of foods high in vitamin B6 at meals for 6 months. After 6 months I suggest you only get Vitamin B6 from your food sources (no greater then 100mg a day) and not from supplementation. The Food sources with lowest amounts are: Peaches, Milk, Peas, Carrots, Ground Beef, Brown Rice, Soybeans, Avocado, Banana, and Turkey. Hope this helped you.

[Renee Radenberg]

Glad I was able to help you.

[gkcasey]

They have been taking regular Multivitamin supplementation as advised by her GP and Naturopath since the birth of her daughter 11 years ago.  Has also been trying to eat a high quality diet.  That is when the problem started.

I have some more information now - it is P5P that is abnormally high so her conversion of B6 by her liver is very effective as well.

I am arranging for her results to be re-examined by the Head of our Local Pathology Company.  An Endocrinologist here who is doing work at the John Curtin School of Medical Research is also going to have a look for research on toxicity at this level.

The highest reading I have found in research is in the order of 1000 units.  Will keep this list posted as it has not only implications here but also for a lot of practitioners out there and for my own clients.

Have sent her your advice and I thank you.  She was in tears and very angry about not having had this diagnosed for her and her daughter earlier.