Supplements cause 'build-up' of vitamin B6 and food does not.
What I'm asking is if there are other causes for B6 build up besides taking supplements.
Vitamin B6 is found naturally in our foods, however, B6 supplements are the main reason for toxicity of vitamin B6. Long term (2+ years) supplementation of 500-5,000mg/day will result in medical issues, such as neuropathy which maybe reversible with discontinuing the supplement and lowering high B6 foods. The recommended daily dose is 1.3mg for men & women ages 19-50 and 1.7 for men >50 years old. Suggest only getting your vitamin B6 from food sources which has the added benefit of fiber, and other vitamins/minerals. Hoped that helped you.