I originally posted back in November regarding my 23 year old son with OCD. I was curious to know if anyone here is resistant to medication for OCD. He is on 300mg of Anafranil since December and started Luvox at the end of December and doctor has been increasing the luvox, so he is now on 300mg of luvox as of two days ago. This is the strange part.....every time the doctor increased one of these meds, my son can feel a difference (thoughts are not that intrusive or severe), but this only lasts about 3-4 days and then he feels that he is back to where he started at the lower dose of 50mg. How is it possible to feel better after the increase, but then that feeling goes away after a few days? As he says, the medication is not working consistently, and these two medications are specifically for OCD. Also, I know therapy is also supposed to be a big help. He went to two different therapist who did not help at all. We are going to a new therapist next week who deals and works with OCD. I know medications work and effect people differently, but why are they not consistent? In the past he was on lexapro, wellbutrin and Zoloft with no relief, that is why he is on anafranil and luvox now. Thanks for listening.