4 chemo drugs down- what's next?

[jane65]

Hi ladies,
I can use a little input and advice.
I've had 4 chemo drugs since I was diagnosed with epithelial OVCA staged 4B,  after surgery.
I've had carbo/taxol, Topotecan, Gemzar and Doxil.

Now it looks like we have to move on to another chemo drug, and I'm seeing my oncologist Monday to discuss a new treatment. Cancer is in the lymph nodes in the pelvic area and surgery is not an option.

What chemo drugs besides the 4 I've had, have been successful for your treatments?

My second question is, if you're on Medicare were you able to get Avastin, and how difficult was it for your oncologist to get it approved?

Thanks for your help, this is really getting discouraging.
Jane

[Jane39]

I echo Pam, I can only imagine how frustrating and just how plain tired you must be.  Your a fighter Jane, you will find the right chemo that will work.  Just wanted you to know that I will keep you in my prayers and send you positive positive energy.  Jane

[silver&gold]

Just wanted to wish you luck in finding the next chemo drug Jane, I will be keeping you in my thoughts and prayers.

Best wishes

Angie

[jr1971]

Hi jane65

Not sure if you are BRAC positive or not? If you are then there is a new breed of treatments called PARP inhibitors which are in trials and seem to be having good results. They inhibit the activity of enzymes known as PARPs (the full name is too complex to write) and this leads to cancer cells dying - they have fewer side effects too as they only target cells which have gene mutations.

Good luck on Monday.