Aa
A new HOPE for us
A TREATMENT for women with advanced ovarian cancer may be near, with Australian researchers developing a drug that stops or slows down the progression of the killer disease.
There is no treatment for women who have become resistant to standard chemotherapy, yet most women diagnosed with ovarian cancer reach this point.
Australian biotechnology company Novogen has developed an experimental drug, phenoxodiol, which restores sensitivity to the cancer cells of patients that have become chemo-resistant.
Paul Mainwaring from Brisbane's Mater Hospital said if the drug was successful, it would revolutionise the way the cancer was treated.
"That's the exciting thing about this drug," Professor Mainwaring said. "If it can affect the way in which the body develops resistance to chemo it will radically alter the way we approach treatment in the future."
Hundreds of women worldwide are trialling the drug as part of the OVATURE (Ovarian Tumor Response) study.
Half the women will receive the tablet as well as weekly platinum-based chemotherapy, while the other half will get a placebo.
The US Food and Drug Administration, has given the trial priority status because it targets an unmet clinical need, meaning the drug could be on the market before the final clinical trial results.
Novogen's research director Professor Alan Husband said three hospitals in Sydney - Prince of Wales, Westmead and Royal North Shore - were recruiting and he hoped to have 95 patients worldwide by the end of the year. The drug could be on the market within 18 to 24 months.
There is no treatment for women who have become resistant to standard chemotherapy, yet most women diagnosed with ovarian cancer reach this point.
Australian biotechnology company Novogen has developed an experimental drug, phenoxodiol, which restores sensitivity to the cancer cells of patients that have become chemo-resistant.
Paul Mainwaring from Brisbane's Mater Hospital said if the drug was successful, it would revolutionise the way the cancer was treated.
"That's the exciting thing about this drug," Professor Mainwaring said. "If it can affect the way in which the body develops resistance to chemo it will radically alter the way we approach treatment in the future."
Hundreds of women worldwide are trialling the drug as part of the OVATURE (Ovarian Tumor Response) study.
Half the women will receive the tablet as well as weekly platinum-based chemotherapy, while the other half will get a placebo.
The US Food and Drug Administration, has given the trial priority status because it targets an unmet clinical need, meaning the drug could be on the market before the final clinical trial results.
Novogen's research director Professor Alan Husband said three hospitals in Sydney - Prince of Wales, Westmead and Royal North Shore - were recruiting and he hoped to have 95 patients worldwide by the end of the year. The drug could be on the market within 18 to 24 months.
Hi, I was going to post that article too, but noticed it already on medhelp in more detail, see this link below. My mother has stage 4 OVCA and is treated by Dr Paul Mainwaring at Brisbane mater. She has been a stage 4 for 3 years and her CA125 is down to 8.
http://www.ovaturetrial.com/patients/index.html?gclid=CO2xguL_s5ICFQY3gwodMgq9RQ
http://www.ovaturetrial.com/patients/index.html?gclid=CO2xguL_s5ICFQY3gwodMgq9RQ
LOL the one I've been promoting for a while now!!! :) :) :)
All it is is the soy isoflavone 'Genistein' that has been tweaked just a little bit. It will make the cancer 'chemosensitive' again to the best drug you can take still...platinum based chemo.
Of course, the natural version does this also but phenoxodiol can also be taken IV (but they are *not* going to market it this way...it'll be in pill form).
I have an article on Genistein if anyone is interested! Shoot me a message.
If you take this trial, you *may* of course get the placebo, but you will also get weekly carbo-p which has also been shown to help fight ovarian cancer even if you are resistant to it. Good bet either way.
All it is is the soy isoflavone 'Genistein' that has been tweaked just a little bit. It will make the cancer 'chemosensitive' again to the best drug you can take still...platinum based chemo.
Of course, the natural version does this also but phenoxodiol can also be taken IV (but they are *not* going to market it this way...it'll be in pill form).
I have an article on Genistein if anyone is interested! Shoot me a message.
If you take this trial, you *may* of course get the placebo, but you will also get weekly carbo-p which has also been shown to help fight ovarian cancer even if you are resistant to it. Good bet either way.
Thats great! i am actually treated at the mater hospital in Brisbane and they do amazing work for ovarian cancer so if anyone will find an answer they will!
I cant have kemo however , does not work for my rare type, hopefully more will be done on the rarer forms too! and to prevent them getting to the advance stages especially when it takes years to turn invasive it is extremely FRUSTRATING sitting and waiting like a ticking time bomb!
I cant have kemo however , does not work for my rare type, hopefully more will be done on the rarer forms too! and to prevent them getting to the advance stages especially when it takes years to turn invasive it is extremely FRUSTRATING sitting and waiting like a ticking time bomb!
Have an Answer?
You are reading content posted in the Ovarian Cancer Community
Learn how to spot the warning signs of this “silent killer.”
Diet and digestion have more to do with cancer prevention than you may realize
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
