I was diagnosed with Stage IIc ovarian cancer five and a half years ago. My pre-surgical CA-125 level was only 57 and I was 46 with no family history of ovarian or any other cancers, so the Gynecology-Oncologist told me the likelihood the tumor was malignant was low. The tumor ruptured a week before my scheduled surgery so an emergency surgery was done followed by six courses of chemotherapy. My CA-125 quickly decreased after surgery ( peaked in the 80's), and has been running from 5.2 to 6.5 for the past five years. My question is this: Since my CA-125 level was never significantly elevated, how much of an increase in the level would indicate a possible recurrence of cancer?
Ca 125 is fairly nonspecific test and can be elevated in many benign conditions (infection, heart disease, liver disease, endometriosis)
Having said that, when you have had a known diagnosis of cancer, the CA 125 becomes a tracker for recurrence.
Some tumors produce alot of this protein. Other tumors such as yours, do not produce high levels. However, in my experience, it is still reasonable to follow it.
For you if you start seeing an elevation relative to your baseline, I would repeat it a few times say once a month.
for instance if it is 5 and then 15 and then 6 and then 10 and then 8 - that is just random lab variation
however if it is 5 then 10 then 20 then 40, that is clearly a trend and a reason to check a CT scan
I am glad you are doing so well.
Copyright 1994-2018MedHelp.All rights reserved. MedHelp is a division of Vitals Consumer Services, LLC.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.