Hello ladies, I am still actually awaiting to hear what my new chemo cocktail will be used this second go around, but it sounds like it might be the carboplatin/gemzar combo. First time I had the Carboplatin/Taxotere, but since 2006 I've had constant lower leg achiness and problems, and oncologist told me that due to these neurapathy problems they won't use the taxotere again. I argued the point where that I will use what ever worked, last combo kept cancer away for 4 years 7 months, but he gave me a look, and said it could do enough damage to my legs where I couldn't use them, so I was like okie dokie. Anyway I am rambling. Just wanted to hear how you ladies that might of had this combo, how you all did? Any major issues? or concerns? I am already assuming the hair will be gone, again. Last go round I had good meds that kept off the nausea, emend, zofran, and steroids, so I have those on board for this go round. Will take any advice anyone will give me. I've heard that if you did relatively well with chemo the first time, you are expected to do the same on subsequent times. I am new at having to do this again. Appreciate your imput ladies. Looks like my first treatment will be the week before Christmas. Merry Christmas to me ;)