Avastin

[ehr]

I have had three cycles of Avastin after Taxol finally stopped working and my CA125 went up up and away. PtCt was clear. The switch to Avastin showing an initial significant drop in my 125 level. However my ;last bloodtest showed a increase in the marker, the current level is still well below where I started from prior to the first cycle. Does anyone on this forum have any experience with Avastin and how it works in connection with CA125. Do results tend to fluctuate or is this just a sign that the drug is not working for me. Its probably too early to tell but I just had to ask. thanks to all

[Helmar]

Hi girls... and thankyou for the input, as I don't know that much about Avastin yet. It's always good to get some info from those who are having it, before fronting up to begin the ordeal. :-)
My CA.125 is a good marker, but it's always in the 100s or 1000s, so I've learned to live with those high numbers.. and have been doing so for 4 years now.
I wish you both all the best with Avastin.. and I hope to hear wonderful news from you both in due course....Hugs to you both...Helen...

[ehr]

Becky what you say is true, minimal side effects in comparison to other treatments I have had and there have been plenty over the last 5+ years, I get 15 mg/kg every 3 weeks so its pretty much the same dosage. My CA125 is very very sensitive it rises and falls quickly. I am hoping that it starts dropping again - what a roller coaster ride this is. Take care - Judy

[Tybear]

Hi there. I'm on Avastin right now. I get 10mg/kilogram of bodyweight and I have my treatments every other week. I have had no side effects as of yet - actually I feel pretty good. I am tired, moreso after the infusion, but it resolves itself after a few days. I also take cyclophosphamide everyday in a pill. No real side effects from that either. I know when you read about Avastin and all of the scary side effects, it's frightening! I still lose sleep over it, but I really feel ok. I'm pleasantly surprised....
I go for my next CT scan on March 25th, and by then, I'll have 4 treatments under my belt. I'll let you know the results when I get them. As for the CA125, it was never a good marker for me and I don't honestly know if they even check it anymore.
Take care,
Becky

[Helmar]

Hello... My Oncol. is talking about Avastin for me later too, so I am interested in hearing anything re side affects etc also. He did say that it seems to work better in combination with another chemo, and suggested Caelyx...but that was only a suggestion. I won't know until we get down to the 'nitty-gritty' and decisons are made.
Please let's know how you go... and I do hope it works for you. Sometimes with some of these drugs, they don't work immediately, and as we are all different, it could take a little more time for you. Wishing you all the best, and good results....hugs...Helen...