713892 tn?1276536344

Pathology Report Question

I've been told that my 15 year old daughter has an immature teratoma - grade 2.
Though no surgical staging was done, there was no gross evidence of implants, peritoneal washings were clear... Post Surgery Diagnosis:  Beign right Mature Teratoma of the ovary.
Post-Op, there were some questions about some of the frozen sections of the cyst, so it was sent off to a separate pathology lab.

In looking at the pathology report, I have some questions about terminologies:

Final Microscopic Diagnosis:
Right Ovary, Cystectomy:
Teratoma with Mature and Immature components.
The Immature components are grade 2 (based on the extent of the immature foci).

In the comment section it states:
Dr. XX described muture components including cartlage, bone, squamous and glandular epithelium, and extensive glial/neural tissue with a high level of organization in some areas resembling gerebellum or other recognizable structures.  The immature neuroepithelial foci seen on several slides, total greater than a 40x microscopic field.  Oncologic consultation is recommended.

Based on my research, Grading is of extreme importance in determining a course of action.
My question is:  Do those comments jive with the final assessment of: Grade 2?
Another question:  Would the Oncologist review the pathology, and verify the grade himself, or would I have to request another pathology report be completed?
Another question (sorry):  How long can a "frozen section" be kept for a pathological review? (ie: when is it too late?)

We have been to a Gyn/Oncologist, and he said in older patients, he would recomend chemo treatment right away (3 rounds of BEP).... After consulting with a pediatric oncologist, they have determined that we will take a "wait and see" approach.  We have monthly appointments set up to do bloodwork, and there will be sonograms and CT scans at regular intervals as well.
2 Responses
178783 tn?1197300099

My daughter was also diagnosed at 15 yrs. old with immature teratoma.  She was stage 3 and grade 3 with implants in her omentum.  Removal of the ovary with the immature teratoma, removal of a mature teratoma on the other ovary, removal of her omentum and many lymph nodes.  She had 4 rounds of BEP chemotherapy.  She is 2 yrs. out from diagnosis and in March will be 2 yrs. from treatment and considered in clinical remission.  Sorry I couldn't answer your questions this time, but if you have any other questions, don't hesistate to ask.  Just thought I would post to share a success story and demonstrate that this type of cancer can be defeated.  I hope that everything works out for your daughter and chemo is not needed.  

Take Care and God Bless,
713892 tn?1276536344


Thank you for taking the time to respond.
I read through your reports of your daughter's chemo treatments when I first found this site about a month ago.  You can't imagine how helpful that it has been to me to know what kind of things might be ahead of us, but ultimately knowing that while it might be difficult, it is certainly cureable.

Looking at Ashley's pictures (seeing the same youthful smile that Alexa has), and reading your story has brought some comfort to me, as I search for answers.  Thank you for taking the time to document it for people like me.

Your story, and Cayden'sMommy's story are the reason that I joined the site.

I've updated my profile, and included a journal entry that is extremely encouraging to me, and might be of some interest to you now..

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