My mom has been fighting OC for over a year and has been on non-stop chemo/treatment since Aug 29, 2008. Anyway, she is currently on Avastin and her numbers are slowly decreasing (but still at ca 1200). Anyway since about mid-June she periodically gets SEVERE back pain. They have done scans, mri, and they look pretty clear. It hits her hard for 3 - 7 days and then recedes. She is currently in another round. Is this normal and a sign of disease progression? Is the only thing that can be done is pain management? Despite disease progression, she has tolerated treatment well and is in generally really good health. She is having a hard time accepting everything the cancer throws at her and HATES to take meds and painkillers. Is it going to get to a point that she has to take daily pain killers just to tolerate the pain. I really have no idea what to expect. I'm not super hopeful for remission at this point, but I guess it is possible. Who knows. Should I brace myself for a new level of pain and struggling for my mom? I can't tell you how p*ssed off this all makes me. I am so angry watching what this unbeleivable disease is doing to my beautiful, life loving, mom. And to all of you in this community. It is just so wrong.