Hello and welcome to the forum. Thanks for your question and we apologize for delay in response! We are glad you are on to maintenance therapy for your previous cancer! Typically, letrozole does have a favorable side effect profile in relation to toxicity. This doesn't mean it is side effect free, however. The trade off is that it does appear affective in terms of prolonging recurrence. As ovarian cancer has such a high recurrence rate, you and your doctor will need to do a risk to benefit analysis regarding what you are experiencing and the desired effect of maintaining your remission. This study talks about the efficacy of using letrozole (femara) in this way. https://www.onclive.com/view/letrozole-maintenance-therapy-improves-rfs-in-ovarian-cancer- 2.5 mg is the typical dose used in studies. What side effects are you experiencing? And what does your prescribing physician/oncologist say?