Aa
ca 125
Dear Doctor just got back from my oncologist . I am one year out of chemo for stge 3 ovarian. when diagnosed my ca was 424 after my chemo 6 iv and 8 ipmy ca was 1.4. It has stayed low and run from 3 to 1.9 current. My question when do you do CAT scans ordo I wait and hope the ca is accurate. He said my exam felt normal, I don't want to sound unaprreciated for the good fortune but also don't want to miss something if it is changeing. My Doctor also mentioned that a cat scan is not that good for early detection especially since I can't use contrast. I am also on AArimidex I am estrogen positive and Braca I mutation. What is your opinion thanks
MEDICAL PROFESSIONAL
here is some of the info from that site
prepared by Dr. Alan Boyar
Radiologists and scientists alike agree that radiation in large doses causes cancer; the current controversy centers on what dose should be considered "acceptable" before cancer risk begins to increase.
Most experts ascribe to the currently accepted linear "no-threshold" theory for radiation carcinogenesis risk, which holds that any radiation dose, no matter how small, can cause cancer, meaning that the risk is never zero. Recently this theory has come into question, with some experts suggesting that the risk of developing cancer after low levels of radiation exposure are overstated. These experts believe that radiation induced cancer risk only increases after the total radiation exposure passes a certain threshold level and that exposure to amounts of radiation below this threshold dosage do not significantly increase the risk of developing cancer. No risk of adverse health conditions has been established for exposures of 5,000 milli-rem (mrem) or less. The Health Physics Society recommends against quantitative estimation of health risk for individual exposures of 5,000 milli-rem in one year or 10,000 milli-rem lifetime. The threshold dose of radiation above which the risk of developing cancer begins to increase is proposed to be about 10,000 milli-rem.
The average person living in the United States is exposed to about 360 milli-rem per year from background sources (3.6 mSv/yr). Background radiation varies substantially from location to location depending on elevation, soil and latitude. For example, a resident of Denver, CO experiences about double the dose of background radiation due to the higher altitude than someone living at sea level. A low risk location's background radiation exposure is about 240 milli-rem/year. The annual limit on public exposure from a single source of ionizing radiation is 100 milli-rem (1mSv). Medical sources are exempt from this limit. The only medical procedure currently subject to a radiation exposure limit is mammography with a limit of 300 milli-rem per procedure.
CT scanning is a relatively high dose procedure that is becoming much more common worldwide. In the mid-1990s, CT scanning accounted for only 4% of the total X-ray procedures done but 40% of the collective dose from all diagnostic X-ray. The introduction of helical, fluoroscopic, and multi-slice CT technology has increased the usage of CT while doing nothing to diminish the radiation dosage. In US hospitals today, CT scanning accounts for about 15% of imaging procedures and 75% of radiation exposure. When multiple CT scans are performed on the same patient, the cumulative absorbed radiation doses rise to the range at which small but statistically significant increases in cancer have been found in the atomic bomb survivors.
Because CT procedures involve far higher radiation exposures than those received in conventional x-ray exams, there is growing worry that such exposure could contribute to the development of a radiation-induced cancer later in life. The FDA is currently investigating this situation. Effective radiation doses from conventional diagnostic CT procedures range from 100 to 4,000 milli-rem, not much less than the lowest doses of 500 to 2000 milli-rem received by Japanese survivors of atomic bombs, who were shown to have a small but increased relative risk for cancer mortality due to radiation exposure. A typical conventional CT scan of the abdomen delivers up to 1000 milli-rem of radiation, equivalent to 500 chest x-rays. Marconi (Marconi Medical Systems, Inc. 595 Miner Road, Cleveland, OH 44143) reportedly has calculated the typical patient dose received when performing their non-FDA approved cardiac calcium scoring protocol when performed on their single slice spiral CT scanner using the Win Dose program. In their cardiac calcium scoring protocol (130 kV, 200 mA, Spiral, 1.25 pitch, 77 images) the effective patient radiation dose delivered to the patient was 4,300 milli-rem, equivalent to over 200 chest x-rays. It would take more than ten years to absorb this amount of radiation from the natural background radiation sources of sun and soil. In contrast, the Electron Beam CT Scanner delivers only about 70 milli-rem of radiation to the patient when acquiring images for the coronary calcium scoring exam.
As a general rule, the electron beam CT scanner delivers only about 20% of the radiation to the patient that a conventional CT scanner would. The primary explanation for this is that the Electron Beam CT scanner is essentially a fast shuttered camera only turning on for brief periods of 50 to 100 milli-seconds as needed to acquire the images. Conventional CT Scanners have an X-ray emitter on one side of the patient and the detector on the opposite side. In this configuration, the X-ray emitter is always on during the acquisition of the image data.
Currently, there are no federal or state regulations for acceptable radiation doses for specific CT examinations in the United States. Physicians referring for or performing CT examinations need to understand the absorbed radiation doses associated with various procedures. When it comes to using radiation for screening or diagnostic purposes, the key is to decide whether its use is justified, then optimize it.
Estimates of radiation exposure are given in rem (radiation equivalent man) which is based on the total amount of X-ray expected to be absorbed by the patient during an average study. (100 milli-rem (or mrem) = 1 mSievert (mSV))
prepared by Dr. Alan Boyar
Radiologists and scientists alike agree that radiation in large doses causes cancer; the current controversy centers on what dose should be considered "acceptable" before cancer risk begins to increase.
Most experts ascribe to the currently accepted linear "no-threshold" theory for radiation carcinogenesis risk, which holds that any radiation dose, no matter how small, can cause cancer, meaning that the risk is never zero. Recently this theory has come into question, with some experts suggesting that the risk of developing cancer after low levels of radiation exposure are overstated. These experts believe that radiation induced cancer risk only increases after the total radiation exposure passes a certain threshold level and that exposure to amounts of radiation below this threshold dosage do not significantly increase the risk of developing cancer. No risk of adverse health conditions has been established for exposures of 5,000 milli-rem (mrem) or less. The Health Physics Society recommends against quantitative estimation of health risk for individual exposures of 5,000 milli-rem in one year or 10,000 milli-rem lifetime. The threshold dose of radiation above which the risk of developing cancer begins to increase is proposed to be about 10,000 milli-rem.
The average person living in the United States is exposed to about 360 milli-rem per year from background sources (3.6 mSv/yr). Background radiation varies substantially from location to location depending on elevation, soil and latitude. For example, a resident of Denver, CO experiences about double the dose of background radiation due to the higher altitude than someone living at sea level. A low risk location's background radiation exposure is about 240 milli-rem/year. The annual limit on public exposure from a single source of ionizing radiation is 100 milli-rem (1mSv). Medical sources are exempt from this limit. The only medical procedure currently subject to a radiation exposure limit is mammography with a limit of 300 milli-rem per procedure.
CT scanning is a relatively high dose procedure that is becoming much more common worldwide. In the mid-1990s, CT scanning accounted for only 4% of the total X-ray procedures done but 40% of the collective dose from all diagnostic X-ray. The introduction of helical, fluoroscopic, and multi-slice CT technology has increased the usage of CT while doing nothing to diminish the radiation dosage. In US hospitals today, CT scanning accounts for about 15% of imaging procedures and 75% of radiation exposure. When multiple CT scans are performed on the same patient, the cumulative absorbed radiation doses rise to the range at which small but statistically significant increases in cancer have been found in the atomic bomb survivors.
Because CT procedures involve far higher radiation exposures than those received in conventional x-ray exams, there is growing worry that such exposure could contribute to the development of a radiation-induced cancer later in life. The FDA is currently investigating this situation. Effective radiation doses from conventional diagnostic CT procedures range from 100 to 4,000 milli-rem, not much less than the lowest doses of 500 to 2000 milli-rem received by Japanese survivors of atomic bombs, who were shown to have a small but increased relative risk for cancer mortality due to radiation exposure. A typical conventional CT scan of the abdomen delivers up to 1000 milli-rem of radiation, equivalent to 500 chest x-rays. Marconi (Marconi Medical Systems, Inc. 595 Miner Road, Cleveland, OH 44143) reportedly has calculated the typical patient dose received when performing their non-FDA approved cardiac calcium scoring protocol when performed on their single slice spiral CT scanner using the Win Dose program. In their cardiac calcium scoring protocol (130 kV, 200 mA, Spiral, 1.25 pitch, 77 images) the effective patient radiation dose delivered to the patient was 4,300 milli-rem, equivalent to over 200 chest x-rays. It would take more than ten years to absorb this amount of radiation from the natural background radiation sources of sun and soil. In contrast, the Electron Beam CT Scanner delivers only about 70 milli-rem of radiation to the patient when acquiring images for the coronary calcium scoring exam.
As a general rule, the electron beam CT scanner delivers only about 20% of the radiation to the patient that a conventional CT scanner would. The primary explanation for this is that the Electron Beam CT scanner is essentially a fast shuttered camera only turning on for brief periods of 50 to 100 milli-seconds as needed to acquire the images. Conventional CT Scanners have an X-ray emitter on one side of the patient and the detector on the opposite side. In this configuration, the X-ray emitter is always on during the acquisition of the image data.
Currently, there are no federal or state regulations for acceptable radiation doses for specific CT examinations in the United States. Physicians referring for or performing CT examinations need to understand the absorbed radiation doses associated with various procedures. When it comes to using radiation for screening or diagnostic purposes, the key is to decide whether its use is justified, then optimize it.
Estimates of radiation exposure are given in rem (radiation equivalent man) which is based on the total amount of X-ray expected to be absorbed by the patient during an average study. (100 milli-rem (or mrem) = 1 mSievert (mSV))
MEDICAL PROFESSIONAL
Hi There,
That is wonderful news. I agree with your doctor. The Ca 125 is really the most sensitive test. I do get an occasional Ct scan. Sometimes having a baseline Ct scan after therapy can be helpful to compare to future scans. having said that, there has been considerable recent discussion about getting too many scans and increasing people exposure to radiation. As a result unless absolutely necessary, many doctors do not get routine scans. I have pasted one interesting site on radiation doses.
take care
http://www.newportbodyscan.com/radiationdosage.htm
That is wonderful news. I agree with your doctor. The Ca 125 is really the most sensitive test. I do get an occasional Ct scan. Sometimes having a baseline Ct scan after therapy can be helpful to compare to future scans. having said that, there has been considerable recent discussion about getting too many scans and increasing people exposure to radiation. As a result unless absolutely necessary, many doctors do not get routine scans. I have pasted one interesting site on radiation doses.
take care
http://www.newportbodyscan.com/radiationdosage.htm
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