inflamed granulation tissue

[jane65]

Good morning, I saw my GYN in April and he thought he saw some abnormal tissue in the vagina and he was concerned that it might be a spread of my OVCA. He took biopsies and thankfully it came back as inflamed granulation tissue.

Since then, I've had a pinkish discharge,  I have an appointment to see him next week, I read about sulfa treatments or possibly cauterizing the area should take care of it.

My question is, since inflammation affects the CA125, can this possibly be the reason my CA has gone up a few points for the past 3 months? My last CT didn't show evidence of cancer.

I'm due to have my CA125 repeated on Monday and I'll ask my oncologist's associate about this, but I was wondering if you had any thoughts.

I'd hate to start a new chemo regime based on the CA results if it goes up again, and it's due to inflammation, not cancer.
Jane

[jane65]

Thanks Becky,
I'm seeing my oncologist Monday, and my GYN on Thursday so we'll have the answers next week.
I believe that inflammation, or infection can affect the CA125 reading, when you call to get the results of your biopsy, ask for your own information. Definitely call to find out what the biopsy showed, I'm sure you want to know the results and I really hope it's only granulation tissue.

Thanks for the info about silver nitrate, I'm sure he'll treat it and clear it up.

I hope you're feeling well today, it's been a rough time for you, and you know how much we all care for you.

Talk to you soon,
xoxo
Jane

[Tybear]

Sorry...I meant to add that yes, they use silver nitrate sticks to cauderize the tissue. They had to do this with some granulation tissue that developed around my nephrostomy incision..it didn't hurt, but stung for a little bit. Granulation tissue bleeds very easily and after the silver nitrate treatment, I've had no problems. (although it did discharge for a good few days afterwards)
Becky

[Tybear]

Hi Jane...
I posted earlier in the week about the exact same thing although my gyne was fairly certain it was tumor spread and not granulation tissue - I guess I should call and get the results of the biopsy to double check that. I don't know how much that would affect your CA125? I mean, if it's coming through the vagina, then wherever it's inflamed on the inside you can bet it's just as inflamed on the outside as well (I would think). I'd be curious to know if your doctor thinks the CA125 increase could be from just that...hopefully, that's all it is.
I too, would hate to start a treatment based soley on your numbers when there's no evidence of disease...
Good luck...and let us know how you make out.
Becky