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2016728 tn?1328358841

Might be an answer to some

Hi I have been reading a lot of these post and have been through similar situations drug screens turning up a false positive /neg. Do all of you know and I found this out the hard way. That certain herbal an supplements can affect your drug results. If you eat poppy seeds or anything of that sort u need to do research because if u r tested for heroine and have not taken any.....and have just eaten something with poppy seeds u will test positive for heroine poppy seed
Heroine can be derived from poppy seeds.
This concept is tricky that's why u have let ur dr know everything ur taking and I mean everything ,if u eat something unusual u tell the dr. This is what it's gotten to. The brats on the st that want to abuse this stuff has made it hard for the people who need it.
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Avatar universal
The original poster made a comment, they did not ask a question. No one said their "post" was insignificant. It was said that their "information is insignificant and incomplete". I do not see that as being rude at all. It's very important that we get the correct information not only on this forum but all of the forums here.
The rules are the same for all of us. No one has any special privileges.
Helpful - 0
7721494 tn?1431627964
Are you prescribed Welbutrin (bupropion)? How about phentermine (Ionamine)?

Have you used an OTC cold/flu medication containing pseudoephedrine or phenylpropanolamine lately?

How about a sinus inhaler like Vicks Vapor Inhaler?

Any of these situations can cause false positives for amphetamines. These cases are documented in the medical literature -- all a PCP need do is search a medical reference source like Pubmed.

Simply put, physicians are not trained in the advanced pharmacology and pharmacokinetics needed to understand either false positives or false negatives that can occur with immunoassay UDT.

The immunoassay method used for UDT in most doctor's offices are cheap, but inaccurate. One reason they cause false positives is that immunoassay cannot determine the difference in enantiomers because of loss of chirality in an ion source (your doctor should understand this sentence).

Samples that test positive for illegal drugs, or negative for prescribed drugs, should be sent to a medical laboratory for chromatographic analysis for an accurate result.

There is also a new app available from Remitigate.com that can help a physician understand the many unexpected results in UDT.

Don't lose your access to pain medication due to a faulty UDT -- educate your prescriber about these issues.

A simple internet search for "false positive UDT amphetamine" will bring up enough resources to convince your doctor to look further into the realities of UDT.
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Avatar universal
I have had a false positive on my last UA, for cocaine and amphetamines.  I have NEVER touched an illegal drugs or substance in my life.  The only drugs I take are what is prescribed to me by my pm.   No one can explain this to me and I am determined to find out what is going on.  One of my medications is methadone 5 mg 2x daily.  The same UA, showed negative for Methadone but positive for EDDP, which is the metabolite of Methadone.  You cannot have one without the other.   I have had several UA, in the course of 9 years that have returned questionable results.   At this time I am looking for a lab, not affiliated with this dr and have my UA done there.
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Avatar universal
You do have a good point. I apologize if I misread the post and came off wrong. It is a good idea to essentially keep a running diary in your head of what you have taken (did you just finish a course of antibiotics or take some cold medication, etc? -if so when?), along with anything that you think may be relevant to the test or that you are concerned may cause an inaccurate result. It is better to be safe than sorry. As things get more regulated and harder on patients and clinics, it is best to be safe than sorry. I apologize if my post seems insensitive. That was not my intention at all.

I hope things get better for you.
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Avatar universal
Good answer philnoir.

You cannot beat a GC/MS test. Period. I am not making any accusations, so don't get me wrong. Immunoassays can cross react with other substances. The rate is higher with different tests. Every drug has different metabolites. If you truly believe that you have a false positive UDS, then you should discuss it with your physician. My physician randomly sends off specimens to a lab for quantitative testing and confirmation. The insurance EOB i noticed was that the test cost $4000+. Of course, the insurance only paid usual and customary charges, and I was not responsible for the rest. The poppy seeds are rather irrelevant. They can check if that was the cause it it is sent off to the lab. Physicians usually know what the levels and metabolites are anyway.

I recommend you consider which you value more, different foods with poppy seeds, or pain management. If it were me, I would skip the poppy seed muffin or bagel. It is just not worth the hassle.


*Disclaimer: I am not a doctor, I am not your doctor and This is not medical advice.*

Hope things work out.
Helpful - 0
7721494 tn?1431627964
Thank you. Don't know what you've read, but your information is insignificant and incomplete.

UDT is performed by two methods -- immunoassay and chromatography.

Immunoassay is a quick and inexpensive test that uses colored reagent strips, either on a bottle or in a test strip, to detect specific chemical substances.

Immunoassay gives a yes/no answer. Your sample is either present for a subtance or not.

So-called wide-screen UDT search for a variety of psychactive subtances -- opioids, benzos, MJ, PCP, other recreational drugs.

False positives and false negatives are common with immunoassay -- by 50% or more according to some surveys. OTC medications and other substances can skew the values, or create false positives. Individual metabolism can cause false negatives.

People who risk dismissal from a pain practice for "failing" a UDT that utilizes immunoassay should talk with their doctor, who may or not be aware of the high risk of false results with this test method. There is medical literature availble about the problem, and now even an app is available to help docs interpret false UDT results. Refer your doctor to Remitigate.com for more info.

Chromatography is a precise lab test that looks for the specific metabolites of any medication, and can determine dose and medication of that medication within reasonable time periods. There are very few false results from chromatography, certainly no false opioid positives for someone who's had a poppy seed bagel, or false MJ readings for someone taking omeprazole.

Dr offices and pain clinics use immunoassay because it is cheap and quick. Chromatography is expensive and requires a medical laboratory, expensive equipment, and skilled medical lab scientists to perform the tests.

People who experience false negative/positive results with immunoassay UDT should refer their doctor to the medical literature on immunoassay anomaly and demand a retest using chromatography. Or send him to the website, www.remitigate.com

BTW, the opioid drug diacetylmorphine aka heroin is spelled without a trailing 'e'. The word heroine, is the feminine form of the word hero, and refers to the female protagonist in Victorian era literature, aka the writings of Jane Eyre.
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