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1310633 tn?1430227691

Starting Efexor (Neurontin Didin't Work)

So I tried Neurontin for my chronic-pain, with zero results except for a weight-gain of 2 lbs in the 3 weeks I was on it. I titrated up to the recommended 2700mg's/day, to no avail.

Saw my PM today and she took me off Neurontin and put me on Efexor. Does anyone have any experience with Efexor for chronic-pain?
8 Responses
547368 tn?1440545385
Hi EL,

I hope you will have better result with Venlafaxine (Effexor or Efexor) than you have had with Neurontin. I did try Neurontin but I too had no noticeable pain releif with it. I have not used Efexor but I can provide you with a bit of information.

Efexor, if I have my facts straight was initially manufactured and used as an antidepressant and since has proven to have other actions.

Neurontin and Efexor are chemically different. Efexor is a structurally novel Serotonin-Norepinephrine Reuptake Inhibitor which is chemically unrelated to other antidepressants. Studies indicate that Efexor has an analgesic effect that is independent of its antidepressant activity; however, the mechanism of this effect is not yet clear.

In my opinion anything (with in reason) is worth a try when your pain is severe. Some ppl have great pain releif on one medication while others experience no pain releif.

I hope you will share with us the effectiveness and your experience with Efexor. We all learn from one another. We will look forward to hearing from you again soon.

Take Care,

535089 tn?1400677119

I don't have information for you but, if you do a web search, you will find all of the info you need. Just enter the name of the drug.

Good luck,
Avatar universal
I do take it but wish I had never started.I take neurontin as well and have changed my mind the in the past couple of months.I think that it is beneficial in my pain management.
655875 tn?1295698707
Good luck with the Efexor.  I could not take the Neurontin due to being overly sensitive to the med and developing a very big rash(with a single 300mg dose).  I never tried the Efexor.  I hope this is something that works.  
82861 tn?1333457511
Neurotontin - ACK!  There's a reason it's also called "morontin" by the unfortunates who don't do well with it.  Like me.  LOL!  That junk totally vaccumed my brains out and didn't do squat for pain.  I don't have typical nerve pain like an impinged nerve, so I was kind of surprised when the doc wanted to try it.  Had to look like a compliant patient though and spend a month in misery.  

Then there was another med in the same category that I can't even remember now.  Started with a "t" maybe?  The first titer did nothing.  The second titer did nothing for pain but my face, hands and feet started tingling.  The third titer did nothing for pain and everything I put in my mouth tasted like arse, my tongue was paralyzed, couldn't feel my hands and feet and finally lost fine motor control.  Topomax!  That was it.  It took several weeks after discontinuing that stuff for the side effects to depart.  Never again.  No more "nerve" meds for me!
172023 tn?1334675884

Know what you mean....I love the name Morontin!!!  

To the OP (probably long gone by now):
It took me a full 2 months and tripling of the dosage to have a decent result with it.  I'm still on it.  
Avatar universal
I hope you're feeling better! I've been thinking about u a lot and hoping you're recovering well!
1401023 tn?1280784958
I was on Effexor for severe depression in '08.  Read up on withdrawal going off the drug.  I had to go off a couple mths after I started b/c I fell pregnant, ended up in miscarriage prob. not due to the med.  I had low progesterone.  Anyway, read up on the nasty symptoms people have had going off...
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