One night in May 2006, I noticed that my right calf seemed to be swollen. It was not painful, just felt heavy. I thought it might be a DVT. It was late and I had no desire to go to the ER, so I took 2 aspirin and went to bed. The next morning, the swelling was gone, but I went to see my GP anyway. She sent me for an ultrasound, which showed nothing. A blood test showed that I had Factor V Leiden (heterozygous). I continued to take aspirin for two weeks and had no recurrence to date, despite several very long distance flights. A couple of months ago, I was diagnosed with essential hypertension and started on perindopril 4mg at night. I have a Mirena IUD for contraception. I love it, because I have been period free since 2000. I had the second one fitted in 2005. I am 47, a non-smoker, fit, and my BMI is 24, but I have a family history of hypertension - dad had 1st MI at 40, quit smoking, but died of second MI at 54; mom diagnosed with HT at 54, still doing great on meds at 75. My questions:
1) Is it OK to keep Mirena with HT and history of DVT?
2)Is it possible that the progesterone from the Mirena made me prematurely hypertensive? With my family history, I expected that it would happen in my 50's, but not yet, especially since I have always been careful about my diet, weight and exercise.
3) For about 3 years, I have noticed persistent numbness in my toes and balls of my feet, as well as sometimes cold, white toes, which always get better with a warm bath. What causes this?
I am disappointed that all my hard work to stay healthy seems to have been in vain, as my "bad genes" are catching up with me anyway.
Thank you for your time.