cvs testing

[Cheekylady]

Hi im 34 and 12 + 3 weeks pregnant with my first baby. My husband and i have just received the devastating news that our baby is at high risk of downs syndrome, 1 in 131 chance. We have been referred for cvs testing next week so just wandering if anyone on here has had this test done and what the odds and results were? We're trying to stay positive but its hard. Thanks x

[NatFox]

Fantastic!!

[ShePowell]

Brilliant so pleased for you :-D

[Cheekylady]

Thanks for all the comments. We had the tests done yesterday and we're over the moon to tell you that our baby is ok, 23 pairs of chromosomes and everything looks good on the scan so we can breathe a sigh of relief x

[ShePowell]

Hi Cheekylady, have these comments reassured you at all? I hope they have x

[adgal]

I have done a bit of reading on the MaterniT21 test.  How very exciting!!  As far as I know it's not yet available in Canada, but hopefully it will be shortly.  I sure wish it had been available when I was pregnant.  Fantastic that science has come up with a non invasive accurate test.  

And saraanon is so right. I know so many women from this board who had far higher risk level then you have and all has been fine.  

[saraanon]

I had a 1:11 risk for trisomy 13 and 18 and 1:17 for downs.  I opted for the MaterniT21 test and it came back all normal.  I just had my 20 week anatomy scan and baby looks good, no markers, everything measuring the way it's supposed to.  The odds are in your favor here.  When I was researching the MaterniT21 test I saw that LOTS of women get high risk ratios ( a lot higher than yours)  on that 12 weeks screening and the majority come back just fine with a healthy baby.  Good luck.

[naturschld]

Ask your Dr about the MaterniT21 test.  Here is some info from their site:

We are proud to offer our patients an exciting new testing option called MaterniT21 Plus. This prenatal screen is a new blood test offered through Sequenom Center for Molecular Medicine. This screen is designed to detect increased amounts of material from chromosome 21 (Down syndrome), chromosome 13 (trisomy 13) and chromosome 18 (trisomy 18) and requires only a maternal blood sample after 10 weeks of gestation. At this time MaterniT21 Plus screening is available to patients meeting one or more of the following criteria:

•Advanced maternal age (35 years or older at the time of delivery)
•Family history
•Abnormal prenatal ultrasound findings
•Increased risk based on screening results
The benefit of this screen is the high detection rates and low false-positive rates for these chromosome abnormalities with no risk to the pregnancy.

•99.1% detection for Down syndrome
•99.9% detection for trisomy 18
•91.7% detection for trisomy 13

You can read more on their site. I intend to take this if available in my area.  Good luck to you!

[adgal]

Hi there.  I understand why hearing that is so scary.  When I had my first trimester screen, my son came back with 1:13 odds of DS.  I too was terrified.  I didn't have CVS, but I did opt for amnio.

So, a bit of information it's important to have.  First off, the first trimester screen is in no way, shape or form a diagnostic test.  Its only purpose is to give you your odds, and then allow you and your Dr. to determine whether or not further testing is required.  When you put it into perspective, it is pretty unlikely that you are carrying a ds child.

CVS and Amnio are both invasive tests.  Both carry the possibility of complications, one of which can be miscarriage.  Stats on CVS are 1:300 of a loss, with amnio it's 1:400.  So although it's unlikely, the possibility is always there.

If you opt to move forward as i did, don't be afraid to ask a lot of questions of the Dr. performing the test.  I practically interviewed mine..lol.  I wanted to know experience level and how many incidents that particular Dr. had had.  By the time I was done my interview, I felt very comfortable and confident.

So remember I told you my son's first trimester screen (blood/u/s combo) came back with 1:13 odds?  Well, today I have a happy, healthy, completely typical 3 year old little boy.  The amnio showed that he was typical, and I was able to enjoy the rest of my pregnancy without worry.  So for me, I have no regrets.  

I am neither pro nor anti invasive testing, but believe firmly it is a very personal choice that each couple should make for themselves.  Oh, and you might hear that knowing the outcome shouldn't matter.  That too is for you to decide, and only you.

All the best to you.

[stacey10]

1 in 131 chance  still is good odds in your favour, the majority of the time baby is fine, did they do u/s combined with blood tests? those two together are alot more accurate than just the u/s alone....cvs can be abit uncomfortable and in some places have about a 1-2% risk of miscarriage, it all depends on the skill of the doctor doing the procedure, just make sure to rst afterwards and keep your fluid intake up, good luck :)

[ShePowell]

Hi there, I don't know too much on the subject, but your baby has a 130 out of 131 chance of not having downs! They seem like pretty high odds in your favour to me x