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High FSH (need advice)

I'm new at this and have never posted anything online but I recieved devastating news last week from my ob-gyn and am so confused. I am 30 years old and my husband and I decided to it's time to have children. I haven't been trying but went to my doctor for my annual and discussed my plans so she set up some testing and gave me some good tips on health and fitness. Well to my surprise I got a call a week later that my fsh came back at 23. She said she had not expected it and that I need to see a RE. I am completely regular every 28 day and alway have been. I have been using the OPK packs for the last 2 months and detect a LH surge on day 13. My estradiol came back normal at 27.160. Also I did a fertell test at home on day 14 that came back negative. I know FSH fluctuates but I thought I'd for sure test positive. From my understanding midcyle fsh is usually higher. I just wonder about lab error. My sister and mother took a while to get pregnant I guess from what they say. It's hard to stay positive with all the negative stuff out there about FSH over 20. I know this is wishful thinking but does anyone know or hear of lab errors. My doctor said the hole picture didn't look right and something seemed off. She did say she felt I could concieve but it may be more difficult and that although I tested high it may be an indication of low quantity not low quality given my age. If anyone has any insight, advice, opinons or encouragement I'd love to hear it. I'm a runner too and recently changed my excercise routine so it's not so harsh on my body. I have extremely low fat for a girl and am muscular.. just born that way.. never lifted a weight. Sometimes I wonder about my hormones..
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Avatar universal
Hi Ally,
My FSH level was 23 and then 45! They took two readings - the Clomid Challenge test. My RE told me I would never have my own baby. He said high fsh levels meant low quality and/or low quantity (I'm 43) and mine were way too high. He basically kicked us out of the office at that point, offering only egg donation or adoption as our choices. I started acupuncture and herbs and found a new RE. Our new RE doesn't place as much emphasis on FSH levels as he does on age. FSH levels can vary dramaticallty from cycle to cycle. Also you never know what is 'normal' for you compared to the standard normal. He said FSH levels might play a role, but they also might not. He gave me a 5-10% chance of getting pregnant based solely on my age. We were considering IVF, and deciding on my eggs or donor eggs, and started to save money to do either. Two months later I was pregnant! I know that the acupuncture and herbs played a huge role. So did the hope that the second RE gave us. Sadly, I lost the baby at 8 weeks, due to a chromosomal abnormality (the most common reason for miscarriage). The important thing is, that I got pregnant, and on my own!! So you hang in there, think positive, and consider some alternative treatments to strengthen your body/organs, etc. in conjunction with your medical treatments. Your age is a great benefit - you haven't reached that "advanced material age" yet, where the odds of pregnancy start to drop. And a second opinion is always a good idea too. See if you can find an RE that works with women with high FSH levels. Good luck to you and your husband!
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Avatar universal
Wow, it feels good just to hear from someone experiencing the same thing. I really appreciate your note. I have an appointment to see a RE on Dec. 2nd and certainly have a lot of questions for him. I am so happy for you that you were able to concieve! You don't realize what a miracle they are until you have  difficulty actually conceiving. I am feeling optimistic about my chances and more positive than negative so that's a start. I've gotten in touch with a accupuncturist and changed my diet. I start accupuncture 12/12 and have heard great things about him. He specializes in infertility. I'm so lucky to have a  husband that is so wonderful and supportive. He always knows the right things to say! I'm lucky in that sense. We just started trying about 2 months ago but that may not even count bc we never bd during ovulation due to his job. He is a Pro Hockey Ref and always seems to be away at that important time. Next month he'll be in Cleveland and this times he's bringing me with him.. I appreciate you note sincerely.. Thank you Wendy
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Avatar universal
I would also go to a Reproductive Endocrinologist as soon as possible, as an RE can help you maximize your chances each cycle.  Your FSH score indicates egg quantity and is only helpful if the test is run on day 2 or 3 of your menstrual cycle (you don't say what day you were tested).  A high score doesn't mean you can't get pregnant, but it may take longer and possibly require ivf.  At least your eggs are still young, so you will have options!  It is better to be under 35 with a high FSH score than to be older with a relatively low score (which is my situation).  But I would still see an RE asap, especially if you want more than one child.
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Avatar universal
My RE says that age trumps fsh numbers every time. You are still young, so I would say that you have a decent chance at getting pg. I was 34 when I got my high fsh result. Went on to get pg and have twins. Don't give up. Just find a RE that you trust (even if that means seeing a few of them before you decide on one). The RE makes all the difference in success.
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Avatar universal
If I were you, I'd talk to a RE asap. I'm 41 and I was told I had a high FSH (at last test it was 9.5). I think in my case age is more of a factor than FSH.

Like everyone is telling you, don't give up. See a good RE. Exercise, eat right and PRAY!!!

Peace.
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Avatar universal
I'm going through treatment where I've done one cycle of clomid and it didn't work. For the first time since I started seeing a specialist,my FSH level is 17, all other times it was under 10 around 8 or 9. My husband and I have opted to try IVF. Our specialist says even with on high reading it reduces the chance of getting pregnant even with IVF. I'm 33 but since I heard the news feeling down. Reading the above comments gives me hope. Any advice or thoghts
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Avatar universal
HI, I am 35, going to be 36, Already had two UNsuccessfull IVF cycles, My RN said, he will do more testing, and with blood work, he concluded that my FSH is 11 and my odds of getting pregnant is almost none to 1.   I am on my third cycle and he said I don't even want me to try for anything as its not going to work.
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332747 tn?1198120117
Wow, FSH of 11 doesn't sound all that bad, especially at your age.   FSH does seem to be the magic bullet doesn't it?  I'm 42 with an FSH in March of this year @3!  Then by golly, I decide to ttc and suddenly my FSH jumps to 25 following the Clomid Challenge Test.  I think Clomid really does something drastsic to mess with our FSH levels.  I don't think enough data has been collected or studies done of the effects Clomid has on women over 40 years of age.  It really messes with us I think.  

We all deserve BFP's and babies in our arms.  May the universe sway our way.

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Avatar universal
SHP
I went to an RE this March after trying naturally for 2 years.  I will be 40 this coming Feb.  On my 3 day clomid challenge my FSH was14.9.  I got the speach about how this would be nearly impossible.  We tried IUI 3 times with only 1 egg produced each time no matter what injectibles were used.  We called off IVF this October after again only 1 egg.  I was ready to go to a donor egg when my RE wanted to try a protocol that he had used only a handful of times on women with high FSH but all had been successful.  Monday we retrieved 7 eggs - all mature.  6 fertilized - 2 stopped growing.  Today 4 good 8 cell embryos were implanted.  I know that the chance of this working out is small but we have to trust in a higher power about this all.  I want you to know that women with high FSH can conceive.  My RE said that there are several of his clients pregnant right now.  They are learning more and more all of the time.  good luck to you all and please pray for me.
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332747 tn?1198120117
You have my prayers that this works for you.

My FSH on cd 3 was only 16. I say "only" because compared to cd 10 of 25, 16 seems rather low.  l.o.l..   I'll be going to a specialist in Jan..  He is the director of fertility at a teaching/training/research hospital in my area.  They are sort of renouned around the country for innovative research and healing.  What sort of protocol did you try?  

I'm very happy to hear about your success with IVP this time around.  Please keep us up to date so we can rejoice with you.
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Avatar universal
SHP
16 is not bad.  I have no idea what my day 10 was.  I heard that day 3 is the important number.  They have got to move aggressively with you though.  Tell them that you want to be aggressive - it takes months trying different things with a high fsh.

I was so convinced that I would be the exception on the egg reserve.  Of course the RE was correct.  He started me on FSH injectibles, then added and changed combos.  We tried drugs from Europe first (they were the cheapest) then we finally wound up with American drugs.  The European ones gave me more reactions than the American.  They have to start small to see how you react to the drugs.  They also don't want to over stimulate you. I guess we are all a lab experiment until the right combo is found.  The final round that gave me the great result started with 5 days of 5mg Clomid, then adding Gonal F (high dosages) and Menopur.  On day 10 Antagon was added.  The whole protocol was 14 days.  Before we had only gone 5 to 7 days on everything.  All I can say is that this worked.  It woke my ovaries up and that is what I needed. The Embryologist told me that the four embryos implanted looked as good as a twenty year old's.  Of course they cannot see if they are competely normal.  The RE implanted four since the odds were so low that they would implant.  I would love twins but am praying for one healthy one.  Like I said, the few women (all high fsh) that he has used this on are all pregnant with the exception of me.  (We will know in 2 weeks.)  He only does this protocol when all else fails.  My ovaries were very sore for the 4 days after egg retrieval.  Who cares - all we want with high fsh is some eggs and the chance to see if one will implant.  If this doesn't work I will give it to God.  I am so thankful to even have the chance to see if they will implant.  

Everything that I had read told me that clomid didn't work well for women over 40.  The key to my 7 eggs was the combo of the clomid and injectables.  It is like the clomid stimulates them but they can't really grow - then the injectables pump them up.  So far my RE has 100% sucess on the egg part.  It was a lot of drugs but I am thankful.


My RE was at the teaching hospital in my state for a long time but recently split and has his own practice.  His teacher once told me that we all have to remember that man can only do so much - that God is in this too.  

There is always the donor egg.  I will do that if all else fails.  I am just thankful for the chance right now.

Good luck to you.  The RE's always give you the worst news - they have to.  The more I learn the more I realize how little any of them know.  They are however learning more each day.    
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332747 tn?1198120117
Wow, thank you for the information.  I'll mention this protocol to the RE when I go in.  I won't be able to proceed if this moves to donor eggs, and am not completely sure I will be able to even if it goes to IVF.  IVF is just so expensive and I'm doing this solo, no insurance or spousal support.   Maybe, God willing I'll meet the man of my dreams and marry in 08 and then can pursue aggressively donor eggs or whatever it takes!  For now, I'm living my life as if children won't be a part of it.  Trying to make peace with that so if it happens, WOW won't I be blessed!!!! But, if it doesn't, I'll have a plan and purpose for my life that satisfies me.

I'm so happy for you that you retrieved 7 eggs!!  WOW!  100% success rate, it doesn't get better than that.  You're right the side affects from injectables is a small price to pay for a baby.

Thank you for sharing your story.  I am wishing lots and lots of sticky, sticky baby dust your way. I have good feelings about this for you!
Lisa

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Avatar universal
I read your info regarding the protocol with much interest.  I have a question -- Is the Clomid dose 5mg or 50 mg?  Thanks
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332747 tn?1198120117
That is a great question!  I just assumed it was a typo and should have been 50mg Clomid.  I'm glad you asked about it.  IIt just sounds so amazing that the RE has had 100% success rate. I can't wait to hear back from SHP. (-:
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Avatar universal
SHP
I had to go double check but it was only 5mg.  I have taken the 50 in the past.  With 14 days the RE can't stimulate you too quickly.  I guess that the 5mg just wakes you up for all of the injectibles to follow.  

He has only tried this on 4 women counting me.  I hope that I do not screw up his stats.  Of course at this point he says that if they don't make it my age is a factor.  Let's face it - the eggs have to be normal- all the Dr. can do is make us produce them.  What if they are chromosomally screwed up - they won't attach or I will loose them.  Man can only do so much.  

Lisa,  I feel for you.  I only got married 3 months ago.  Before this was all my little red wagon.  My husband (then boyfriend) was dead set against having any children for 5 years.  (If he had not made me wait we might not be in this pickle.)  Pray for this.  I did.  I prayed that God would change his heart.  I am not a religious person but I couldn't move a mountain.  One night he came to me and told me that he had changed his mind.  Pray and try everything you can.  The money has been hard to come by but we have figured it out.  We will be paying for years though.  No guaranteed results either.  If this never happens we will eventually adopt.  

Good luck to you all.  I may go crazy with worry until that darn Preg test.
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332747 tn?1198120117
Wow, your story is very close to mine.  I had always made a deal with myself that if I was single by the time I reached 39, I would look into donor sperm and be inseminated.  Well, it just so happens - the year I turned 39,  I began dating someone who was 10 yrs younger (29) than I and had 2 children from a previous marriage.  DEAD SET agains having any more children.  Also told me if I were to go to a clinic for a sperm donor he would leave me.  He would always tell me "you are so young you've got plenty of time to have children". I checked with my Nurse Practitioner at the time (she'd done all my gyno stuff for like 20 years), about looking into sperm donors, and she also told me, "No need to be in such a hurry, you've got plenty of time.  My mom had me at 48 and she wasn't even trying to get pregnant". So, I thought - "Oh, o.k. I'll just wait until things(boyfriend) in my life are ready, then I'll start ttc".  Well, to make a long story short - now I'm 42 and just happened to stumble upon  a book on pregnancy after 40 in the bookstore.  I wasn't shopping for a pregnancy book, the cover as I was passing the isle just caught my eye.   So, I picked it up and began thumbing through it.  It listed all the statistics and decline of fertility beginning at 35, but dramatically declining at 42 until by the time your 43 pregnancy is extremely rare, and more than likely impossible.    I had this epiphany and thought "OH MY GOD, I'm 42!!!!  I don't have any time to waste."  Boyfriend or not, I'm going to ttc!!   As a result I did lose the boyfriend and here I am now ttc and realizing my FSH is not on my side.  All of my sisters, aunts, cousins are exteremely fertile.  They get pregant on the 1st try each time they try up until the age of 40.  None of them had tried after 40.  But, they all told me, "Oh we are so fertile you'll get pregnant.  Don't you dare go on fertility drugs because with our family history you'll have multiples for sure!".  Anyhow, so it came as a big surprise to me that this was going to be a challenge.  I haven't shared with my family the results yet, I just want to keep this private for now.

Well, this has been a very long post!  You are so right, God is ultimately who decides when life will be created.  I am learning to give up what I can't control and make peace with it.  But, that doesn't mean I won't try like crazy to control the factors that are in my control.  
I'm looking forward to reading about your BFP soon!!!!
Lisa
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332747 tn?1198120117
How long have you  been ttc?  What is your FSH?  (sorry if that's too personal - you can just say none of my bees wax - if you want.)  (-:  
I'm so glad you asked the question about 5mg versus 50mg.  I would have just assumed it was 50 and gone be bopping into my dr with the wrong protocol.  
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Avatar universal
SHP
I hate the comments that people give.  They are so insensitive.  "Don't go to a Dr. and spend the money - just relax and it will happen naturally."  Women our age (I'll be 40 in Feb.)  can't relax when we have been failing for so long and know that there is an egg problem - and if it had happened naturally we wouldn't have gone to a doctor.  "If you quit trying you will get pregnant."  How do you quit trying or thinking about it when you have a limited window left to try in?  

My favorite is when my friends (also in their late 30's or early 40's) tell me that I can some of thier eggs that they are "very fertile."  I laugh and tell them that their eggs are as old as mine and they keep insisting that they are fertile.  Of course none of them have been tested or pregnant in over 10 years.  They get insulted that I would not want their scrambled eggs.

Tomorrow will be 1 week from the embryo transfer.  Yesterday I cheated and took a preg. test and it showed a very very faint line.  That one was a Clear Blue Easy.  Today I cheated and used a Walgreen's early detection and there was no line at all.  I shouldn't have done it but I was going crazy.  I may go crazy more now.  Without thinking I drank a large glass of tea yesterday.  The caffine had me shaking as I am not used to it anymore.  I turned red in the face and got very nervous.  I hope that I didn't do anything to myself.  

Anyhow- I understand how irritating it is when family members and friends tell you that you are fertile when you have been told otherwise.  I just want to say "why can't you just say that you are sorry for me and to hang in there."  It makes me feel oh so alone.
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332747 tn?1198120117
Yes, people can be so insensitive!  My ex-boyfriend used to tell me, "look you've got a wonderful dog and lots of kids in your classroom, that should be enough for you."  Can you imagine.  A dog!  Yes, he is a wonderfule Border Collie that I love dearly.  But, he's not a flippin human, he's not a baby I can hold, nurse, nurture and raise.  Of course this man has 2 children and can have as many more as he chooses.

I'm sorry to hear about your BFN!  But, getting the faint line one day, that's a good sign. (unless you had a HCG trigger - could still be in your system)  But otherwise a faint line is a line, is a line!!!  

Someone on the fertility forum gave me a website of a clinic in NY that has donor egg profiles with photos listed.   I didn't realize you can share a cycle with another person and split the cost!  I guess they get so many follicles (dam* young women) (-:  That there are left overs to split with another person.  Anyhow, after looking at the profiles I'm not so afraid of donor eggs should it come to that.  And splitting a cycle with someone can make the cost more affordable.  

Well, I've got to wait until the 10th of Jan. before I have my appt with the fert. specialist.  I can feel those eggs drying up as I type this. URG!!

Let me know how things turn out for you.  If you're interested in the website, let me know.
Lisa
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Avatar universal
SHP
My mother in law has said to me that my husband's nieces and nephews need a good Aunt.  That may be true but she had 3 children - and 5 grandchildren.  She doesn't know the feeling of not having your own family.  I have had a niece for 30 years.  I love her and we are very close but I just want my own family.  Some people tell me that people live perfectly good lives without children.  Of course these are the people who have them.  The friends that I have who are the most comfort are the ones in their 50's who tried and never had any.  Yes they led wonderful lives but none of them tell me that.  They just say that it wasn't in the cards for them and that they hope that we are successful and that yes it is painful.    

I don't think that the faint line was the HCG since it had been 9 days since the shot.  I am just praying that either the Clear Blue is more sensitive or something.  I was not supposed to test for another week.  I was told that if any of the eggs did attach it would have been this past Saturday or Sunday.  I should have just left it at the faint line and waited.  Sometimes they attach for a while and then don't make it.  I have not given up hope - yet.  Lets hope that the Walgreens brand is just not sensitive enough.  That ice tea did frighten me.  I just didn't think and I have never had such a reaction.  My heart raced for 3 hours.  It was racing and then it dawned on me that I shouldn't have had it.  Again, I guess that if one of these embryos is meant to make it they will.  If God wants you to be here a glass of ice tea shouldn't make a difference.  

I will ask my RE about splitting the cycle.  He is the best around and since I live a few blocks away I don't want to change Doctors.  I had never thought of splitting one.

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332747 tn?1198120117
I haven't had the trigger shot yet, but I've read a lot about it on this forum.  I think 9 days is too early.  It stays in your system 10 - 14 days.  Typically when you have the trigger you are asked to wait 14 days so you won't get a false pos..  I KNOW IT'S TORTURE!   So, I don't think your BFN on cd 10 was accurate.  It may just be to soon to tell at the moment.  
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Avatar universal
SHP
I used to test early after IUI just to see when the HCG really did clear and mine was always gone by day3 or 4.  I was always so shocked.  We did IUI  6 times.  I know that everyone is different though.  

Yes it is making me pretty crazy right now.  My mom is in the hospital and is very ill in another town.  If I knew that I wasn't BFP I could go and try to take her home.  (She has cancer - of all things ovarian - and had 3 strokes- is paralyzed on one side and now has a colostomy)  I just can't deal with her 24 hour care (she is heavy and has to be lifted) until I find out one way or another as I would have to stay with her for a while.  I just can't go picking up a 160 lb woman when they told me not to lift heavy objects right now.  Everything is just so up in the air.  

It was easy the day or two after they transferred the embryos.  I knew that they were floating around for a day or two alive.  That was a special feeling.  They even gave me the most beautiful photos of them before they implanted them.  Now they could be with me or gone.  I am ready to know.
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332747 tn?1198120117
I don't know if you saw my other post, but my appt. with the fertility specialist is tomorrow!  It got bumped up from Jan. 10.   So, tomorrow is the day I get started on the next leg of this journey.

I'm so very sorry to hear about your Mom.  It seems that there is never a good time to ttc.  Life is just full of curve balls!  I hope you get some information soon regarding BFP versus BFN.    Do you have siblings, or dh that can help with Mom's condition?  

Lisa
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Avatar universal
SHP
It takes a village when someone gets old is all I can say.

That is fantastic about your appointment.  Just get ready- the RE is not going to give you much hope.  They never do.  Just let him or her know that you have to go through the steps that you can so that you won't look back in regret.  The stats are against you.  They are against all of us in our position.  Just don't let their attitude get you down.  Let him/her know that you completely understand the stats but that you want to do this.  Someone gets to win the lottery - just get your ticket and try.  If you want your own child you must try what you can.  My cousin did all of this and never had a biological child but it made adoption so much easier to embrace.  She has no regrets.

Also - be aggressive.  If you don't do well with clomid - move on.  Don't waste months trying one thing.  I personally think that my eggs are tough and don't want to be fertilized.  It didn't matter how many eggs came down they couldn't be penetrated.  We did ICSI to make sure they fertilized.  

Don't let the RE get you down.  People with high FSH do have babies.  The percentage is just low.  Again - someone is going to get the golden ticket - it can be you.

Good luck and I will pray for you.

Sylvia

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