Ive been using EPO since 30 weeks and started taking them vaginally last 4 days. Today i decided to use a tampon to help insert the epo to get closer to cervix, as it it difficult for me to reach. Within 10 minutes of inserting the EPO i started get the shakes and hot flashes. Then i felt nauseous and felt the urge to have a bm at the same time. So i sat on the toilet, i threw up everything i consumed this morning but had no bm. As i got up to wipe i noticed I lost my complete mucus plug. No contractions or cramps of any sort, just a little pressure and shooting pains in my pelvis. Im not concerned with the mucus plug comming out, but more of the rapid onset of vomiting and shakes. It all lasted 20 mintues, came and gone. Anyone ever experience that right before labor?